Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21001389 | 0.85 | LIG1 (0.33) | LIG1ACHE | |
| SCHEMBL22614840 | 0.72 | LIG1 (0.31) | LIG1 | |
| SCHEMBL5200877 | 0.70 | LIG1 (0.32) | LIG1ACHE | |
| SCHEMBL21001032 | 0.70 | LIG1 (0.32) | LIG1ACHE | |
| SCHEMBL5200793 | 0.68 | LIG1 (0.32) | LIG1ACHE | |
| SCHEMBL15083749 | 0.67 | CYP19A1 (0.32) | — | |
| SCHEMBL506194 | 0.66 | ACHE (0.41) | LIG1ACHE | |
| SCHEMBL24475286 | 0.66 | CYP3A4 (0.33) | LIG1 | |
| SCHEMBL5200872 | 0.66 | CYP3A4 (0.33) | LIG1 | |
| SCHEMBL5202819 | 0.65 | LIG1 (0.30) | LIG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411110-B1 | Spiro compounds as perfuming ingredients | FIRMENICH & CIE (CH) | 2007-08-22 | — | — | EP | claimed |
| US-7256170-B2 | Spiro compounds as perfuming ingredients | FIRMENICH SA (CH) | 2007-08-14 | — | — | US | claimed |
| EP-1411110-A1 | Spiro compounds as perfuming ingredients | FIRMENICH SA (CH) | 2004-04-21 | — | — | EP | claimed |
| US-20040072721-A1 | Spiro compounds as perfuming ingredients | FIRMENICH SA (CH) | 2004-04-15 | — | — | US | claimed |
| WO-2019101821-A2 | USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR | FIRMENICH SA (CH) | 2019-05-31 | — | — | WO | disclosed |
| EP-1411110-B1 | Spiro compounds as perfuming ingredients | FIRMENICH & CIE (CH) | 2007-08-22 | — | — | EP | disclosed |
| US-7256170-B2 | Spiro compounds as perfuming ingredients | FIRMENICH SA (CH) | 2007-08-14 | — | — | US | disclosed |
| EP-1411110-A1 | Spiro compounds as perfuming ingredients | FIRMENICH SA (CH) | 2004-04-21 | — | — | EP | disclosed |
| US-20040072721-A1 | Spiro compounds as perfuming ingredients | FIRMENICH SA (CH) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072721-A1 | Spiro compounds as perfuming ingredients | SORD, PIR, AKR1C4 | LIG1 3962/4885ACHE 1585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.