SCHEMBL21001032

SCHEMBL21001032

CC1=CC(C)C2(CCCC(C)(C)C2=O)C1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LIG1 P18858 1/20 0.32
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30879573 0.85 LIG1 (0.31) LIG1
SCHEMBL22614840 0.85 LIG1 (0.31) LIG1
SCHEMBL5200075 0.85 LIG1 (0.31) LIG1
SCHEMBL5202819 0.78 LIG1 (0.30) LIG1
SCHEMBL24475286 0.72 CYP3A4 (0.33) LIG1
SCHEMBL5200872 0.72 CYP3A4 (0.33) LIG1
SCHEMBL21001389 0.71 LIG1 (0.33) LIG1ACHE
SCHEMBL5199847 0.71
SCHEMBL22614866 0.71
SCHEMBL5199259 0.70 LIG1 (0.32) LIG1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250066690-A1 Spiro Compounds as Malodor Counteracting Ingredients FIRMENICH SA (CH) 2025-02-27 US claimed
CN-116763963-A Spiro compounds as malodor counteracting ingredients 弗门尼舍有限公司 2023-09-19 CN claimed
US-20230233425-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR FIRMENICH SA (CH) 2023-07-27 US claimed
US-20230159853-A1 SPIRO COMPOUNDS AS MALODOR COUNTERACTING INGREDIENTS FIRMENICH SA (CH) 2023-05-25 US claimed
US-20200345601-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR FIRMENICH SA (CH) 2020-11-05 US claimed
EP-3713610-A2 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR Firmenich SA (CH) 2020-09-30 EP claimed
EP-3713609-A2 SPIRO COMPOUNDS AS MALODOR COUNTERACTING INGREDIENTS Firmenich SA (CH) 2020-09-30 EP claimed
CN-111432851-A Use of volatile ingredients to limit or eliminate perception of malodour 弗门尼舍有限公司 2020-07-17 CN claimed
WO-2019101821-A2 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR FIRMENICH SA (CH) 2019-05-31 WO claimed
WO-2019101814-A2 SPIRO COMPOUNDS AS MALODOR COUNTERACTING INGREDIENTS FIRMENICH SA (CH) 2019-05-31 WO claimed
EP-4707270-A2 SPIRO COMPOUNDS AS MALODOR COUNTERACTING INGREDIENTS Firmenich SA (CH) 2026-03-11 EP disclosed
EP-4632382-A2 METHOD OF IDENTIFYING LAUNDRY MALODOR, MOLDY MALODOR AND/OR SWEAT MALODOR MODULATING COMPOUNDS Firmenich SA (CH) 2025-10-15 EP disclosed
EP-3713609-B1 SPIRO COMPOUNDS AS MALODOR COUNTERACTING INGREDIENTS FIRMENICH & CIE (CH) 2025-08-06 EP disclosed
US-20250066690-A1 Spiro Compounds as Malodor Counteracting Ingredients FIRMENICH SA (CH) 2025-02-27 US disclosed
US-12180434-B2 Spiro compounds as malodor counteracting ingredients FIRMENICH SA (CH) 2024-12-31 US disclosed
CN-111295204-A Spiro compounds as malodor counteracting ingredients 弗门尼舍有限公司 2020-06-16 CN disclosed
WO-2019101814-A2 SPIRO COMPOUNDS AS MALODOR COUNTERACTING INGREDIENTS FIRMENICH SA (CH) 2019-05-31 WO disclosed
WO-2019101821-A2 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR FIRMENICH SA (CH) 2019-05-31 WO disclosed
WO-2019101821-A2 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR FIRMENICH SA (CH) 2019-05-31 WO disclosed
WO-2019101814-A2 SPIRO COMPOUNDS AS MALODOR COUNTERACTING INGREDIENTS FIRMENICH SA (CH) 2019-05-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066690-A1 Spiro Compounds as Malodor Counteracting Ingredients LPO, SORD, FOXO1 LIG1 3614/4885ACHE 81/4885
US-20200345601-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR TAS2R8, TRPA1, TAS2R10 LIG1 4002/4885ACHE 26/4885
US-20230233425-A1 USE OF VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE THE PERCEPTION OF MALODOR TAS2R8, TRPA1, TAS2R10 LIG1 4002/4885ACHE 26/4885
US-12180434-B2 Spiro compounds as malodor counteracting ingredients LPO, SORD, FOXO1 LIG1 3614/4885ACHE 81/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.