Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | GCGR | P47871 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5199254 | 1.00 | NPC1 (0.37) | NPC1RAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL5200686 | 0.86 | KDM4E (0.49) | NPC1RAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL5197710 | 0.83 | KMT2A (0.48) | MEN1ALDH1A1MAPTKMT2AFABP4 | |
| SCHEMBL5197704 | 0.83 | KMT2A (0.48) | MEN1ALDH1A1MAPTKMT2AFABP4 | |
| SCHEMBL5196158 | 0.78 | LSS (0.34) | NPC1RAB9AALDH1A1HPGDCYP2C19 | |
| SCHEMBL5200281 | 0.77 | LSS (0.33) | NPC1RAB9AALDH1A1HPGDCYP2C19 | |
| SCHEMBL5197840 | 0.74 | MAOB (0.37) | MEN1MAPTKMT2ASMN1; SMN2MAPK14 | |
| SCHEMBL5197836 | 0.74 | MAOB (0.37) | MEN1MAPTKMT2ASMN1; SMN2MAPK14 | |
| SCHEMBL5330737 | 0.72 | CNR1 (0.39) | BRAFMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5198712 | 0.71 | TEK (0.48) | KDM4EMEN1ALDH1A1KMT2AFABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846389-A1 | IMIDAZOLE DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006082002-A1 | IMIDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-08-10 | — | — | WO | disclosed |