SCHEMBL51993

SCHEMBL51993

Cc1cn([C@H]2CC(O)[C@@H](CN)O2)c(=O)[nH]c1=O

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TK1 P04183 5/20 0.65
POLB P06746 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13589374 1.00 TK1 (0.65) TK1POLB
SCHEMBL9483871 1.00 TK1 (0.65) TK1POLB
SCHEMBL51992 1.00 TK1 (0.65) TK1POLB
SCHEMBL16480963 1.00 TK1 (0.65) TK1POLB
SCHEMBL16693741 1.00 TK1 (0.65) TK1POLB
SCHEMBL24233253 1.00 TK1 (0.65) TK1POLB
SCHEMBL6063494 0.99 TK1 (0.63) TK1POLB
SCHEMBL5293362 0.95 TK1 (0.60) TK1POLB
SCHEMBL655193 0.90 TK1 (0.67) TK1POLB
Doxribtimine SCHEMBL9222730 0.89 TK1 (0.71) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 441 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1339402-B1 AZAPHENANTHRIDONE DERIVATIVES AND THEIR USE AS PARP INHIBITORS EISAI INC (US) 2010-08-25 EP claimed
US-20060003987-A1 Compounds and their uses GUILFORD PHARMACEUTICALS, INC. (US) 2006-01-05 US claimed
WO-1996039183-A9 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY OF EFFECTOR MOLECULES 1997-01-30 WO claimed
WO-1996039183-A1 COMPOSITIONS AND METHODS FOR TARGETED DELIVERY OF EFFECTOR MOLECULES FRED HUTCHINSON CANCER RESEARCH CENTER (US) 1996-12-12 WO claimed
US-4093716-A Compositions containing 5-amino-5-deoxythymidine and pharmaceutically acceptable salts thereof RESEARCH CORPORATION (US) 1978-06-06 US claimed
JP-1250393-A None JP disclosed
US-12054768-B2 Methods for detecting agglutination and compositions for use in practicing the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-08-06 US disclosed
EP-4123031-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME The Regents of The University of California (US) 2023-01-25 EP disclosed
EP-3283638-B1 METHODS FOR DETECTING AGGLUTINATION AND USE OF KITS IN PRACTICING THE SAME UNIV CALIFORNIA (US) 2022-06-08 EP disclosed
US-20210403978-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-12-30 US disclosed
US-11149296-B2 Methods for detecting agglutination and compositions for use in practicing the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-10-19 US disclosed
US-10774105-B2 Phosphoroamidate esters, and use and synthesis thereof STRATOS GENOMICS, INC. (US) 2020-09-15 US disclosed
WO-1988008419-A1 OLIGOBIPYRIDINE LIGANDS, PROCESS FOR OBTAINING THEM AND APPLICATION AS COMPLEXING AGENTS COMPAGNIE ORIS INDUSTRIE S.A. (FR) 1988-11-03 WO disclosed
EP-0270651-A1 NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. CALIFORNIA INST OF TECHN (US) 1988-06-15 EP disclosed
US-4730001-A HERPES VIRUS SOUTHERN RESEARCH INSTITUTE (US) 1988-03-08 US disclosed
WO-1988000201-A1 NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES CALIFORNIA INSTITUTE OF TECHNOLOGY, INC. (US) 1988-01-14 WO disclosed
US-4710492-A MURINE LEUKEMIA, SARCOMA AND AIDS VIRUSES YALE UNIVERSITY (US) 1987-12-01 US disclosed
US-4128639-A ANTICANCER RESEARCH CORPORATION (US) 1978-12-05 US disclosed
US-4093716-A Compositions containing 5-amino-5-deoxythymidine and pharmaceutically acceptable salts thereof RESEARCH CORPORATION (US) 1978-06-06 US disclosed
US-4093716-A Compositions containing 5-amino-5-deoxythymidine and pharmaceutically acceptable salts thereof RESEARCH CORPORATION (US) 1978-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060003987-A1 Compounds and their uses PARP1, PARP2, PARP3 TK1 1899/4885POLB 112/4885
US-10774105-B2 Phosphoroamidate esters, and use and synthesis thereof PNP, RNGTT, TYMP TK1 71/4885POLB 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.