Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 4/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | WNT1 | P04628 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200577 | 0.90 | TGFBR1 (0.53) | TGFBR1ATMWNT1DYRK1A | |
| SCHEMBL5229192 | 0.90 | TGFBR1 (0.62) | TGFBR1WNT1DYRK1A | |
| SCHEMBL5197782 | 0.88 | TGFBR1 (0.43) | TGFBR1 | |
| SCHEMBL5228132 | 0.86 | TGFBR1 (0.44) | TGFBR1 | |
| SCHEMBL5198925 | 0.83 | TGFBR1 (0.49) | TGFBR1 | |
| SCHEMBL5228813 | 0.81 | TGFBR1 (0.50) | TGFBR1 | |
| SCHEMBL5222935 | 0.80 | TGFBR1 (0.51) | TGFBR1 | |
| SCHEMBL5197993 | 0.80 | TGFBR1 (0.77) | TGFBR1 | |
| SCHEMBL5226839 | 0.79 | TGFBR1 (0.67) | TGFBR1DYRK1A | |
| SCHEMBL5197802 | 0.79 | TGFBR1 (0.62) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275968-A1 | Substituted Biphenyl Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-11-29 | — | — | US | disclosed |
| EP-1798229-A1 | SUBSTITUTED BIPHENYL DERIVATIVE | Sankyo Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275968-A1 | Substituted Biphenyl Derivative | COL2A1, COL1A1, FGFR3 | TGFBR1 40/4885KDM5B 275/4885ATM 4814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.