Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29079294 | 0.82 | ALDH1A1 (0.43) | ALDH1A1TSHRKIF11KCNH2CHRNB2 | |
| SCHEMBL7001869 | 0.82 | KIF11 (0.44) | ALDH1A1TSHRKIF11KCNH2 | |
| SCHEMBL5198366 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3337526 | 0.72 | ALDH1A1 (0.54) | ALDH1A1TSHR | |
| SCHEMBL5200003 | 0.72 | ALDH1A1 (0.54) | ALDH1A1TSHRHTTHDAC2 | |
| SCHEMBL16626142 | 0.72 | ALDH1A1 (0.54) | ALDH1A1TSHRKIF11HDAC2 | |
| SCHEMBL5200151 | 0.72 | ALDH1A1 (0.48) | ALDH1A1TSHRKIF11CHRNB2CHRNB4 | |
| SCHEMBL5198309 | 0.71 | ALDH1A1 (0.43) | ALDH1A1TSHR | |
| SCHEMBL7069678 | 0.71 | CYP2C9 (0.50) | ALDH1A1TSHRKIF11HTTTRPA1 | |
| SCHEMBL14269138 | 0.70 | MAPK1 (0.44) | ALDH1A1KIF11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481981-B1 | Styrene hypophosphite adduct, preparation thereof and use | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2007-08-15 | — | — | EP | disclosed |
| EP-1481981-A2 | Styrene hypophosphite adduct, preparation thereof and use | Clariant GmbH (DE) | 2004-12-01 | — | — | EP | disclosed |