Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14269138 | 0.85 | MAPK1 (0.44) | KIF11MAPK1ALDH1A1KCNN4KCNH2 | |
| SCHEMBL5793925 | 0.84 | TSHR (0.58) | TSHR | |
| SCHEMBL5200155 | 0.82 | ALDH1A1 (0.46) | KIF11TSHRALDH1A1KCNH2 | |
| SCHEMBL14269137 | 0.80 | NCF1 (0.36) | KIF11MAPK1KCNN4KCNH2TAAR1 | |
| SCHEMBL11248540 | 0.79 | KIF11 (0.41) | KIF11MAPK1TSHRALDH1A1KCNN4 | |
| SCHEMBL9647561 | 0.79 | SMN1; SMN2 (0.45) | MAPK1ALDH1A1KCNH2ALOX15 | |
| SCHEMBL238217 | 0.79 | KIF11 (0.41) | KIF11MAPK1TSHRALDH1A1KCNN4 | |
| SCHEMBL9614597 | 0.79 | ALDH1A1 (0.44) | KIF11MAPK1TSHRALDH1A1KCNN4 | |
| SCHEMBL5972484 | 0.79 | KIF11 (0.43) | KIF11MAPK1ALDH1A1KCNN4KCNH2 | |
| SCHEMBL2328171 | 0.79 | KIF11 (0.41) | KIF11MAPK1TSHRALDH1A1KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4973735-A | INSECTICIDE | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-11-27 | — | — | US | claimed |
| EP-1305026-A2 | BARBITURIC ACID ANALOGS AS THERAPEUTIC AGENTS | Novuspharma S.p.A. (IT) | 2003-05-02 | — | — | EP | disclosed |
| WO-2001093841-A2 | BARBITURIC ACID ANALOGS AS THERAPEUTIC AGENTS | NOVUSPHARMA S.P.A. (IT) | 2001-12-13 | — | — | WO | disclosed |
| EP-0220907-B1 | PROCESS FOR THE PREPARATION OF 1,6-DICHLORO-1,6-DIDEOXY-BETA-D-FRUCTOFURANOSYL-4-CHLORO-4-DEOXY-ALPHA-GALACTOPYRANOSIDE | McNeilab, Inc. (US) | 1993-01-20 | — | — | EP | disclosed |
| US-4801700-A | Process for the preparation of 1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α- | MCNEILAB, INC. (US) | 1989-01-31 | — | — | US | disclosed |
| EP-0220907-A2 | Process for the preparation of 1,6-dichloro-1,6-dideoxy-beta-D-fructofuranosyl-4-chloro-4-deoxy-alpha-galactopyranoside | McNeilab, Inc. (US) | 1987-05-06 | — | — | EP | disclosed |