Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 1/20 | 0.56 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.56 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.56 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31321719 | 0.83 | AKR1C3 (0.65) | PLAAT3PLAAT5PLAAT2PLAAT4ALOX5 | |
| SCHEMBL15548241 | 0.81 | ALOX15 (0.68) | KMT2APPARGPPARALTA4HTRPV1 | |
| SCHEMBL28040073 | 0.81 | KMT2A (0.57) | PLAAT3PLAAT5PLAAT2PLAAT4ALOX5 | |
| SCHEMBL28283295 | 0.81 | AKR1C3 (0.64) | ALOX5AKR1C3KMT2AHPGD | |
| SCHEMBL15559089 | 0.80 | ALOX15 (0.74) | KMT2APPARGPPARALTA4HTRPV1 | |
| SCHEMBL15557423 | 0.79 | ALOX15 (0.72) | PPARGPPARALTA4HTRPV1ALOX15 | |
| SCHEMBL15558883 | 0.79 | ALOX15 (0.72) | PPARGPPARALTA4HTRPV1ALOX15 | |
| SCHEMBL14880259 | 0.78 | KMT2A (0.57) | PLAAT3PLAAT5PLAAT2PLAAT4AKR1C3 | |
| SCHEMBL490871 | 0.78 | ALOX5 (0.76) | PLAAT3PLAAT5PLAAT2PLAAT4ALOX5 | |
| Phenyl Propionic Acid SCHEMBL28541899 | 0.78 | KMT2A (0.63) | PLAAT3PLAAT5PLAAT2PLAAT4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633695-A4 | SMOOTH MUSCLE SPASMOLYTIC AGENTS | BRIDGE PHARMA INC (US) | 2007-12-12 | — | — | EP | disclosed |
| EP-1633695-A2 | SMOOTH MUSCLE SPASMOLYTIC AGENTS | Bridge Pharma, Inc. (US) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004105692-A2 | SMOOTH MUSCLE SPASMOLYTIC AGENTS | BRIDGE PHARMA, INC. (US) | 2004-12-09 | — | — | WO | disclosed |