Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.54 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.54 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.54 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.54 |
| ▸ | REN | P00797 | 1/20 | 0.52 |
| ▸ | CTSD | P07339 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040730 | 0.83 | EPHX2 (0.53) | KMT2AMEN1 | |
| SCHEMBL28040077 | 0.82 | TUBB4A (0.54) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL28439801 | 0.82 | AKR1C3 (0.54) | KMT2AAKR1C3ALOX5ALDH1A1HPGD | |
| SCHEMBL28040076 | 0.82 | KMT2A (0.61) | KMT2AMEN1ALDH1A1L3MBTL1HPGD | |
| SCHEMBL490871 | 0.82 | ALOX5 (0.76) | KMT2AALOX5PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL31321719 | 0.82 | AKR1C3 (0.65) | KMT2AAKR1C3ALOX5MEN1PLAAT3 | |
| Phenyl Propionic Acid SCHEMBL28541899 | 0.82 | KMT2A (0.63) | KMT2AALOX5MEN1PLAAT3PLAAT5 | |
| SCHEMBL8122320 | 0.81 | AKR1C3 (0.60) | KMT2AAKR1C3ALOX5ALDH1A1L3MBTL1 | |
| SCHEMBL5200490 | 0.81 | PLAAT3 (0.56) | KMT2AAKR1C3ALOX5PLAAT3PLAAT5 | |
| SCHEMBL8604705 | 0.80 | CYP19A1 (0.70) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175262-A | Chrysotoxine bibenzyl derivative and preparation method and application thereof | UNIV CHINA PHARMA | 2015-12-23 | — | — | CN | claimed |
| CN-105175262-A | Chrysotoxine bibenzyl derivative and preparation method and application thereof | UNIV CHINA PHARMA | 2015-12-23 | — | — | CN | disclosed |