Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL579635 | 0.88 | ABCB1 (0.45) | SIGMAR1ABCB1STAT3 | |
| SCHEMBL30849681 | 0.80 | ABCB1 (0.59) | ABCB1 | |
| SCHEMBL3913665 | 0.80 | ABCB1 (0.59) | ABCB1 | |
| SCHEMBL5200538 | 0.79 | PPARG (0.42) | SIGMAR1HTR1A | |
| SCHEMBL5198250 | 0.79 | PPARG (0.42) | SIGMAR1HTR1A | |
| SCHEMBL5200536 | 0.79 | ADRB2 (0.50) | SIGMAR1HTR1A | |
| SCHEMBL580494 | 0.78 | ABCB1 (0.44) | ABCB1 | |
| SCHEMBL5200493 | 0.78 | PPARG (0.47) | SIGMAR1 | |
| SCHEMBL6054839 | 0.75 | IDO1 (0.48) | — | |
| SCHEMBL5198095 | 0.75 | MAPK1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633695-A4 | SMOOTH MUSCLE SPASMOLYTIC AGENTS | BRIDGE PHARMA INC (US) | 2007-12-12 | — | — | EP | disclosed |
| EP-1633695-A2 | SMOOTH MUSCLE SPASMOLYTIC AGENTS | Bridge Pharma, Inc. (US) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004105692-A2 | SMOOTH MUSCLE SPASMOLYTIC AGENTS | BRIDGE PHARMA, INC. (US) | 2004-12-09 | — | — | WO | disclosed |