Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL579636 | 0.88 | ADRB2 (0.50) | ADRB2KDM4EALDH1A1HTR1APPARG | |
| SCHEMBL580491 | 0.88 | ADRB2 (0.50) | ADRB2KDM4EALDH1A1HTR1APPARG | |
| SCHEMBL6367936 | 0.79 | ALOX5 (0.50) | PPARGPPARA | |
| SCHEMBL8534575 | 0.79 | ADRB2 (0.54) | ADRB2KDM4EALDH1A1 | |
| SCHEMBL5200533 | 0.79 | SIGMAR1 (0.46) | SIGMAR1HTR1A | |
| SCHEMBL10235750 | 0.78 | PPARG (0.46) | KDM4EALDH1A1PPARGPPARA | |
| SCHEMBL10235726 | 0.78 | PPARG (0.46) | KDM4EALDH1A1PPARGPPARA | |
| SCHEMBL580495 | 0.77 | RIPK1 (0.44) | ADRB2KDM4EALDH1A1HTR1A | |
| SCHEMBL5198250 | 0.75 | PPARG (0.42) | ADRB2SIGMAR1HTR1APPARGPPARA | |
| SCHEMBL5200538 | 0.75 | PPARG (0.42) | ADRB2SIGMAR1HTR1APPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633695-A4 | SMOOTH MUSCLE SPASMOLYTIC AGENTS | BRIDGE PHARMA INC (US) | 2007-12-12 | — | — | EP | disclosed |
| EP-1633695-A2 | SMOOTH MUSCLE SPASMOLYTIC AGENTS | Bridge Pharma, Inc. (US) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004105692-A2 | SMOOTH MUSCLE SPASMOLYTIC AGENTS | BRIDGE PHARMA, INC. (US) | 2004-12-09 | — | — | WO | disclosed |