Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4811433 | 0.86 | NR3C2 (0.46) | P2RX7RXRARXRBRXRGKCNQ3 | |
| SCHEMBL287631 | 0.84 | RXRA (0.61) | KIF11P2RX7DAORXRARXRB | |
| SCHEMBL12672499 | 0.83 | KIF11 (0.51) | KIF11P2RX7DAORXRARXRB | |
| Hydrochloric Acid SCHEMBL1373105 | 0.83 | RXRA (0.59) | KIF11P2RX7DAORXRARXRB | |
| SCHEMBL27776461 | 0.83 | KIF11 (0.50) | KIF11P2RX7DAORXRARXRB | |
| SCHEMBL16237967 | 0.83 | DAO (0.47) | P2RX7DAORXRARXRBRXRG | |
| SCHEMBL2173469 | 0.80 | MAPK8 (0.44) | DAOKCNQ2 | |
| SCHEMBL11434970 | 0.79 | IDO1 (0.54) | P2RX7 | |
| SCHEMBL2645838 | 0.79 | ALDH1A1 (0.49) | KIF11P2RX7DAOFFAR1CSF1R | |
| SCHEMBL1150357 | 0.77 | MAPT (0.44) | KCNQ3KCNQ2KCNE1KCNQ1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524715-B2 | Phenoxyacetic acid derivatives useful for treating respiratory diseases | ASTRAZENECA AB (SE) | 2013-09-03 | — | — | US | disclosed |
| EP-1817282-A1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | AstraZeneca AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006056752-A1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2006-06-01 | — | — | WO | disclosed |