SCHEMBL5200930

SCHEMBL5200930

Cc1ccc(N(c2ccc(C(C)C)cc2)c2cccc3c2ccc2c4ccccc4ccc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 2/20 0.38
CYP1A2 P05177 3/20 0.37
CYP2D6 P10635 1/20 0.37
GAA P10253 1/20 0.36
CYP2A6 P11509 4/20 0.35
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
CRHR1 P34998 1/20 0.34
MAOA P21397 1/20 0.33
CNR2 P34972 2/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 3/20 0.33
HSD17B10 Q99714 2/20 0.33
SIGMAR1 Q99720 1/20 0.33
HPGD P15428 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
TSHR P16473 1/20 0.32
CNR1 P21554 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL462137 0.90 HPRT1 (0.47) HPRT1CYP1A2CYP2A6MAOAL3MBTL1
SCHEMBL16716223 0.88 GAA (0.36) CYP1A2CYP2D6GAACYP2A6SLC6A2
SCHEMBL14069675 0.85 SIGMAR1 (0.43) CYP1A2CYP2D6GAACYP2A6SLC6A2
SCHEMBL21348037 0.85 SIGMAR1 (0.43) CYP1A2CYP2D6GAACYP2A6SLC6A2
P-Cymene SCHEMBL10828913 0.84 HPRT1 (0.54) HPRT1CYP1A2GAACYP2A6SLC6A2
P-Cymene SCHEMBL10999791 0.84 HPRT1 (0.54) HPRT1CYP1A2GAACYP2A6SLC6A2
SCHEMBL13338895 0.83 SIGMAR1 (0.44) CYP1A2CYP2D6GAASLC6A2SLC6A4
SCHEMBL17917232 0.83 CRHR1 (0.33) CRHR1CNR2CNR1
SCHEMBL13338853 0.82 SIGMAR1 (0.43) CYP1A2CYP2D6GAACYP2A6SLC6A2
SCHEMBL1155625 0.81 CNR2 (0.36) CRHR1CNR2HTTNPSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1860096-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2007-11-28 EP disclosed