Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 3/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200930 | 0.90 | HPRT1 (0.38) | HPRT1CYP2A6CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL12744254 | 0.90 | SIGMAR1 (0.47) | CYP2A6CYP1A2ALDH1A1TSHRSIGMAR1 | |
| SCHEMBL12744248 | 0.90 | SIGMAR1 (0.47) | CYP2A6CYP1A2ALDH1A1TSHRSIGMAR1 | |
| SCHEMBL452290 | 0.90 | SIGMAR1 (0.47) | CYP2A6CYP1A2ALDH1A1TSHRSIGMAR1 | |
| SCHEMBL4895717 | 0.90 | SIGMAR1 (0.47) | CYP2A6CYP1A2ALDH1A1TSHRSIGMAR1 | |
| SCHEMBL17702100 | 0.89 | CYP1A2 (0.42) | HPRT1CYP2A6CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL4545242 | 0.89 | HPRT1 (0.45) | HPRT1CYP2A6CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL4891181 | 0.88 | SIGMAR1 (0.43) | CYP2A6CYP1A2ALDH1A1SIGMAR1RAB9A | |
| SCHEMBL15024820 | 0.88 | SIGMAR1 (0.46) | CYP2A6CYP1A2ALDH1A1TSHRSIGMAR1 | |
| SCHEMBL1753700 | 0.88 | CYP2C19 (0.39) | CYP1A2ALDH1A1TSHRTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200303649-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-09-24 | — | — | US | disclosed |
| US-10727413-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2020-07-28 | — | — | US | disclosed |
| US-10396297-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2019-08-27 | — | — | US | disclosed |
| EP-3114102-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-12-06 | — | — | EP | disclosed |
| US-20170331053-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-11-16 | — | — | US | disclosed |
| US-20170331053-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-11-16 | — | — | US | disclosed |
| US-20170018710-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-01-19 | — | — | US | disclosed |
| US-20170018710-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-01-19 | — | — | US | disclosed |
| US-9235146-B2 | Photoconductor | RICOH COMPANY, LTD. (JP) | 2016-01-12 | — | — | US | disclosed |
| WO-2015131976-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-09-11 | — | — | WO | disclosed |
| US-7112392-B2 | Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge for image forming apparatus using the electrophotographic photoreceptor | RICOH COMPANY, LTD. (JP) | 2006-09-26 | — | — | US | disclosed |
| US-20060014096-A1 | Image forming method, image forming apparatus and process cartridge therefor | RICOH COMPANY, LTD. (JP) | 2006-01-19 | — | — | US | disclosed |
| US-6861188-B2 | Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor | RICOH COMPANY LIMITED (JP) | 2005-03-01 | — | — | US | disclosed |
| US-20040180280-A1 | Electrophotographic photoreceptor, method for manufacturing the electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using the electrophotographic photoreceptor | RICOH COMPANY LIMITED (JP) | 2004-09-16 | — | — | US | disclosed |
| US-20040170911-A1 | Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge for image forming apparatus using the electrophotographic photoreceptor | RICOH COMPANY, LTD. (JP) | 2004-09-02 | — | — | US | disclosed |
| US-20030194627-A1 | Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor | RICOH COMPANY LIMITED (JP) | 2003-10-16 | — | — | US | disclosed |
| US-6596449-B2 | Photoreceptor includes a photosensitive layer including a deactivating agent. | RICOH COMPANY LIMITED (JP) | 2003-07-22 | — | — | US | disclosed |
| US-6492079-B2 | CHARGE TRANSFER COMPOUND; CHARGE GENERATING COMPOUND ON ELECTROCONDUCTIVE SUPPORT | RICOH COMPANY, LTD. (JP) | 2002-12-10 | — | — | US | disclosed |
| US-20020045117-A1 | Electrophotographic photoreceptor, and process cartridge and electrophotographic image forming apparatus using the electrophotographic photoreceptor | RICOH COMPANY LIMITED (JP) | 2002-04-18 | — | — | US | disclosed |
| US-20020028400-A1 | Electrophotographic photoconductor, image forming apparatus, and process cartridge using the photoconductor | RICOH COMPANY, LTD. (JP) | 2002-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10396297-B2 | Materials for electronic devices | DDT, PNMT, COMT | HPRT1 459/4885CYP2A6 518/4885CYP1A2 67/4885 |
| US-20170331053-A1 | MATERIALS FOR ELECTRONIC DEVICES | DDT, PNMT, COMT | HPRT1 459/4885CYP2A6 518/4885CYP1A2 67/4885 |
| US-10727413-B2 | Materials for electronic devices | EED, OCIAD2, JUND | HPRT1 473/4885CYP2A6 770/4885CYP1A2 174/4885 |
| US-20200303649-A1 | MATERIALS FOR ELECTRONIC DEVICES | EED, OCIAD2, JUND | HPRT1 473/4885CYP2A6 770/4885CYP1A2 174/4885 |
| US-20170018710-A1 | MATERIALS FOR ELECTRONIC DEVICES | EED, OCIAD2, JUND | HPRT1 473/4885CYP2A6 770/4885CYP1A2 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.