Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL52117 | 0.88 | SIGMAR1 (0.40) | SIGMAR1CYP2A6MRGPRX4OPRM1OPRK1 | |
| SCHEMBL4437379 | 0.87 | SIGMAR1 (0.53) | SIGMAR1CYP2A6PDE10ATPSAB1PTPRC | |
| SCHEMBL3816494 | 0.85 | SIGMAR1 (0.51) | SIGMAR1CYP2A6PDE10ATPSAB1PTPRC | |
| SCHEMBL28273323 | 0.82 | CYP2A6 (0.51) | SIGMAR1CYP2A6PDE10ATPSAB1PTPRC | |
| SCHEMBL13873189 | 0.80 | SIGMAR1 (0.57) | SIGMAR1CYP2A6PDE10APTPRCPTPN6 | |
| SCHEMBL6002906 | 0.80 | SIGMAR1 (0.54) | SIGMAR1CYP2A6PDE10ATPSAB1PTPRC | |
| SCHEMBL3813009 | 0.79 | SIGMAR1 (0.60) | SIGMAR1CYP2A6PDE10APTPRCPTPN6 | |
| SCHEMBL3816500 | 0.79 | SIGMAR1 (0.56) | SIGMAR1CYP2A6PDE10APTPRCPTPN6 | |
| SCHEMBL47815 | 0.78 | SIGMAR1 (0.54) | SIGMAR1CYP2A6PTPRCPTPN6PTPN11 | |
| SCHEMBL631289 | 0.77 | CYP2A6 (0.61) | SIGMAR1CYP2A6PDE10ATPSAB1PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43676-E1 | Alkyl ether derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2012-09-18 | — | — | US | disclosed |
| US-8129535-B2 | Alkyl ether derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20090111992-A1 | ALKYL ETHER DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111992-A1 | ALKYL ETHER DERIVATIVES OR SALTS THEREOF | AHNAK, NGF, PMP22 | SIGMAR1 1934/4885CYP2A6 3512/4885PDE10A 3978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.