Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27824826 | 0.85 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL5227447 | 0.83 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL27843830 | 0.83 | GRIK1 (0.40) | L3MBTL1NR1H2NR1H3MAOAMAOB | |
| SCHEMBL27824802 | 0.82 | PPARG (0.43) | ALDH1A1MAOAMAOB | |
| SCHEMBL5179763 | 0.75 | CA12 (0.43) | L3MBTL1ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL28790370 | 0.74 | NCOA3 (0.38) | L3MBTL1ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL27843826 | 0.74 | CNR2 (0.37) | L3MBTL1ALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL27843849 | 0.74 | CNR2 (0.37) | L3MBTL1ALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL11747741 | 0.74 | KMT2A (0.59) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14525877 | 0.73 | NR1H2 (0.66) | L3MBTL1ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1829872-B1 | PROCESSES FOR PRODUCTION OF INDOLE COMPOUNDS | NISSAN CHEMICAL IND LTD (JP) | 2015-07-29 | — | — | EP | disclosed |
| EP-1829872-A1 | PROCESSES FOR PRODUCTION OF INDOLE COMPOUNDS | Nissan Chemical Industries, Ltd. (JP) | 2007-09-05 | — | — | EP | disclosed |