Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201047 | 0.83 | L3MBTL1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL6142952 | 0.81 | HPGD (0.57) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL5201509 | 0.79 | TP53 (0.47) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL28853394 | 0.79 | DAO (0.41) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL11747741 | 0.78 | KMT2A (0.59) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL6471856 | 0.76 | MCL1 (0.39) | ALDH1A1KDM4EHPGDHSD17B10MAOA | |
| SCHEMBL13940630 | 0.76 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL28907783 | 0.75 | HDAC10 (0.43) | ALDH1A1KDM4EHPGDHSD17B10NR1H2 | |
| SCHEMBL11745418 | 0.74 | KMT2A (0.54) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL11558606 | 0.74 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1829872-B1 | PROCESSES FOR PRODUCTION OF INDOLE COMPOUNDS | NISSAN CHEMICAL IND LTD (JP) | 2015-07-29 | — | — | EP | disclosed |
| EP-1829872-A1 | PROCESSES FOR PRODUCTION OF INDOLE COMPOUNDS | Nissan Chemical Industries, Ltd. (JP) | 2007-09-05 | — | — | EP | disclosed |