Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226988 | 0.86 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1ESR1ESR2CYP3A4 | |
| SCHEMBL10760022 | 0.86 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1ESR1ESR2CYP3A4 | |
| SCHEMBL7535051 | 0.84 | ESR1 (0.75) | SMN1; SMN2ALDH1A1ESR1ESR2CYP3A4 | |
| SCHEMBL9248118 | 0.84 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1ESR1ESR2CYP3A4 | |
| SCHEMBL2689280 | 0.84 | CA4 (0.56) | SMN1; SMN2ALDH1A1ESR1ESR2CYP3A4 | |
| SCHEMBL12644365 | 0.82 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1ESR1ESR2CYP3A4 | |
| SCHEMBL35881 | 0.82 | ESR1 (0.70) | SMN1; SMN2ALDH1A1ESR1ESR2CYP3A4 | |
| SCHEMBL14910456 | 0.82 | ESR1 (0.70) | SMN1; SMN2ALDH1A1ESR1ESR2CYP3A4 | |
| SCHEMBL2463038 | 0.81 | LTA4H (0.57) | SMN1; SMN2ALDH1A1ESR1ESR2CYP3A4 | |
| SCHEMBL19418715 | 0.81 | CA1 (0.52) | SMN1; SMN2ALDH1A1ESR1ESR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627832-A | Preparation method for synthesizing tenofovir alafenamide by oxidation method | 江西农业大学 | 2019-12-31 | — | — | CN | claimed |
| US-7294684-B2 | Dimeric and polymeric alkylphenol polysulfides | DOVER CHEMICAL CORPORATION (US) | 2007-11-13 | — | — | US | disclosed |
| US-20070093613-A1 | Dimeric and Polymeric Alkylphenol Polysulfides | DOVER CHEMICAL CORPORATION (US) | 2007-04-26 | — | — | US | disclosed |