Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201042 | 0.95 | — | — | |
| SCHEMBL5201556 | 0.95 | — | — | |
| SCHEMBL5200089 | 0.95 | — | — | |
| SCHEMBL5200081 | 0.71 | GRIN2D (0.31) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5199759 | 0.71 | ALOX15 (0.32) | — | |
| SCHEMBL5199070 | 0.66 | — | — | |
| SCHEMBL3866111 | 0.59 | CYP19A1 (0.32) | — | |
| SCHEMBL5199859 | 0.57 | ALOX15 (0.36) | TSHR | |
| SCHEMBL2692225 | 0.56 | GRIN1 (0.42) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL5272465 | 0.56 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411110-B1 | Spiro compounds as perfuming ingredients | FIRMENICH & CIE (CH) | 2007-08-22 | — | — | EP | disclosed |
| US-7256170-B2 | Spiro compounds as perfuming ingredients | FIRMENICH SA (CH) | 2007-08-14 | — | — | US | disclosed |
| EP-1411110-A1 | Spiro compounds as perfuming ingredients | FIRMENICH SA (CH) | 2004-04-21 | — | — | EP | disclosed |
| US-20040072721-A1 | Spiro compounds as perfuming ingredients | FIRMENICH SA (CH) | 2004-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072721-A1 | Spiro compounds as perfuming ingredients | SORD, PIR, AKR1C4 | GRIN2D 4449/4885GRIN3B 4563/4885GRIN1 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.