Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 1/20 | 0.43 |
| ▸ | CDC14B | O60729 | 1/20 | 0.39 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201183 | 0.93 | GGPS1 (0.44) | GGPS1CDC14BCDC14AGPR52ALOX5 | |
| SCHEMBL5906858 | 0.74 | GGPS1 (0.41) | GGPS1GPR52ALOX5ANO1PTPRC | |
| SCHEMBL5906844 | 0.74 | GGPS1 (0.41) | GGPS1GPR52ALOX5ANO1PTPRC | |
| SCHEMBL5906851 | 0.74 | GGPS1 (0.41) | GGPS1GPR52ALOX5ANO1PTPRC | |
| SCHEMBL4269557 | 0.71 | GGPS1 (0.41) | GGPS1GPR52ALOX5ANO1MEN1 | |
| SCHEMBL4265412 | 0.70 | GGPS1 (0.41) | GGPS1GPR52ALOX5ANO1MEN1 | |
| SCHEMBL4459383 | 0.69 | KEAP1 (0.48) | CYP3A4CYP2D6CYP2C9CYP2C19NPSR1 | |
| SCHEMBL1852378 | 0.68 | ALOX5 (0.42) | GGPS1CDC14BCDC14AALOX5MEN1 | |
| SCHEMBL5236456 | 0.68 | PTPN1 (0.47) | PTPN1DUSP3 | |
| SCHEMBL5046221 | 0.67 | ALOX5 (0.47) | GGPS1CDC14BCDC14AALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805159-A1 | SUBSTITUTED CARBOXYLIC ACIDS | The Institutes for Pharmaceutical Discovery, LLC (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006050212-A1 | SUBSTITUTED CARBOXYLIC ACIDS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY LLC (US) | 2006-05-11 | — | — | WO | disclosed |