Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.37 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906851 | 1.00 | GGPS1 (0.41) | GGPS1ALOX5GPR52PPARGPPARA | |
| SCHEMBL5906858 | 1.00 | GGPS1 (0.41) | GGPS1ALOX5GPR52PPARGPPARA | |
| SCHEMBL4265412 | 0.81 | GGPS1 (0.41) | GGPS1ALOX5GPR52PPARGPPARA | |
| SCHEMBL4269557 | 0.80 | GGPS1 (0.41) | GGPS1ALOX5GPR52PPARGPPARA | |
| SCHEMBL4824661 | 0.75 | TDP1 (0.46) | GGPS1GPR52PPARGPPARAGPR34 | |
| SCHEMBL4824666 | 0.75 | TDP1 (0.46) | GGPS1GPR52PPARGPPARAGPR34 | |
| SCHEMBL4265311 | 0.75 | GPR52 (0.42) | GGPS1ALOX5GPR52PPARGPPARA | |
| SCHEMBL5201192 | 0.74 | GGPS1 (0.43) | GGPS1ALOX5GPR52PPARGANO1 | |
| SCHEMBL4459383 | 0.72 | KEAP1 (0.48) | CYP3A4KCNH2CYP2D6CYP2C9 | |
| SCHEMBL4854025 | 0.72 | ALOX5 (0.51) | GGPS1ALOX5PTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060094747-A1 | Substituted carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY, L.L.C. | 2006-05-04 | — | — | US | claimed |
| US-20060094747-A1 | Substituted carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY, L.L.C. | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094747-A1 | Substituted carboxylic acids | PTPRS, PTPRO, PTPRJ | GGPS1 2090/4885ALOX5 1626/4885GPR52 3026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.