Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27394120 | 0.83 | ALDH1A1 (0.41) | TDP1MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL3342681 | 0.83 | TSHR (0.44) | TDP1ALDH1A1HSD17B10MAPTKDM4E | |
| SCHEMBL3348775 | 0.79 | NOTUM (0.43) | POLBKDM4EGAACYP11B1CYP11B2 | |
| SCHEMBL5199499 | 0.79 | — | — | |
| SCHEMBL8782192 | 0.78 | IKBKB (0.53) | KMT2AKDM4ECASP1 | |
| SCHEMBL16766999 | 0.78 | LMNA (0.36) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL1926319 | 0.77 | METAP2 (0.50) | TDP1MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL3442252 | 0.77 | METAP2 (0.50) | TDP1MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL15850229 | 0.77 | AURKB (0.54) | MEN1KMT2AALDH1A1ALOX15HSD17B10 | |
| SCHEMBL20093067 | 0.77 | SYK (0.42) | PDE4APDE4BPDE4CPDE4DAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817379-A2 | PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS | The Procter and Gamble Company (US) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006060564-A2 | PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2006-06-08 | — | — | WO | disclosed |