Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3550632 | 0.87 | LMNA (0.38) | LMNAPOLBHPGDKMT2ARBP4 | |
| SCHEMBL3550630 | 0.87 | LMNA (0.38) | LMNAPOLBHPGDKMT2ARBP4 | |
| SCHEMBL3544419 | 0.86 | PDK2 (0.45) | LMNAPOLBHPGDKMT2ARBP4 | |
| Hydroxyamine SCHEMBL5238906 | 0.81 | LMNA (0.50) | LMNAPOLBHPGDKMT2ARBP4 | |
| Hydroxyamine SCHEMBL5238910 | 0.81 | LMNA (0.50) | LMNAPOLBHPGDKMT2ARBP4 | |
| SCHEMBL3548147 | 0.77 | LMNA (0.48) | LMNAPOLBHPGDKMT2ARBP4 | |
| SCHEMBL3548145 | 0.77 | LMNA (0.48) | LMNAPOLBHPGDKMT2ARBP4 | |
| Hydroxyamine SCHEMBL5236480 | 0.77 | TACR1 (0.43) | POLBCES2 | |
| SCHEMBL3547423 | 0.76 | LMNA (0.47) | LMNAPOLBHPGDKMT2ARBP4 | |
| SCHEMBL3547425 | 0.76 | LMNA (0.47) | LMNAPOLBHPGDKMT2ARBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539744-A4 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARM INC (US) | 2007-06-06 | — | — | EP | disclosed |
| EP-1539744-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004007444-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS, INC. (US) | 2004-01-22 | — | — | WO | disclosed |