Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | RHOC | P08134 | 4/20 | 0.39 |
| ▸ | RHOA | P61586 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3548143 | 0.83 | RHOA (0.45) | TACR1GAACES2RHOCRHOA | |
| SCHEMBL3544517 | 0.82 | PDK2 (0.44) | TACR1GAACES2RHOCRHOA | |
| SCHEMBL5271173 | 0.82 | PDK2 (0.44) | TACR1GAACES2RHOCRHOA | |
| Hydroxyamine SCHEMBL5238906 | 0.80 | LMNA (0.50) | CES2POLB | |
| Hydroxyamine SCHEMBL5238910 | 0.80 | LMNA (0.50) | CES2POLB | |
| SCHEMBL5201383 | 0.77 | LMNA (0.40) | CES2POLB | |
| Hydroxyamine SCHEMBL5270947 | 0.75 | CACNA1B (0.36) | CYP2C9HSD17B10CYP2C19 | |
| Hydroxyamine SCHEMBL5270943 | 0.75 | CACNA1B (0.36) | CYP2C9HSD17B10CYP2C19 | |
| SCHEMBL1534220 | 0.75 | RHOC (0.62) | TACR1RHOCRHOATDP1 | |
| SCHEMBL3552980 | 0.74 | ADCY8 (0.42) | GAARHOACYP3A4CNR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539744-A4 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARM INC (US) | 2007-06-06 | — | — | EP | disclosed |
| EP-1539744-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004007444-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS, INC. (US) | 2004-01-22 | — | — | WO | disclosed |