Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | RBP4 | P02753 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL5238910 | 1.00 | LMNA (0.50) | LMNAPOLBHPGDKMT2ALOXL2 | |
| SCHEMBL201319 | 0.85 | POLB (0.49) | LMNAPOLBHPGDKMT2ARBP4 | |
| SCHEMBL3551395 | 0.85 | POLB (0.49) | LMNAPOLBHPGDKMT2ARBP4 | |
| SCHEMBL3547030 | 0.84 | POLB (0.48) | LMNAPOLBHPGDKMT2A | |
| SCHEMBL3547033 | 0.84 | POLB (0.48) | LMNAPOLBHPGDKMT2A | |
| SCHEMBL5201383 | 0.81 | LMNA (0.40) | LMNAPOLBHPGDKMT2ALOXL2 | |
| Hydroxyamine SCHEMBL5236480 | 0.80 | TACR1 (0.43) | POLBCES2 | |
| SCHEMBL11160910 | 0.80 | KMT2A (0.53) | LMNAPOLBHPGDKMT2ALOXL2 | |
| SCHEMBL3548145 | 0.78 | LMNA (0.48) | LMNAPOLBHPGDKMT2ARBP4 | |
| SCHEMBL3548147 | 0.78 | LMNA (0.48) | LMNAPOLBHPGDKMT2ARBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539744-A4 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARM INC (US) | 2007-06-06 | — | — | EP | disclosed |
| EP-1539744-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | Vicuron Pharmaceuticals, Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004007444-A2 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS, INC. (US) | 2004-01-22 | — | — | WO | disclosed |