Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.68 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.63 |
| ▸ | PDE9A | O76083 | 3/20 | 0.58 |
| ▸ | ESR1 | P03372 | 3/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11339067 | 0.87 | CYP19A1 (0.53) | CYP19A1DYRK1APDE9AESR1ESR2 | |
| SCHEMBL28819042 | 0.86 | ESR2 (0.60) | CYP19A1DYRK1APDE9AESR1ESR2 | |
| SCHEMBL16382906 | 0.82 | HPGD (0.53) | CYP19A1DYRK1APDE9AMAOAMAOB | |
| SCHEMBL1606265 | 0.82 | CYP11B2 (0.61) | CYP19A1DYRK1APDE9APDE10ADHODH | |
| SCHEMBL28842406 | 0.82 | DYRK1A (0.49) | CYP19A1DYRK1APDE9APDE10ADHODH | |
| SCHEMBL15058476 | 0.78 | HTR1A (0.55) | DYRK1AIMPDH2ALDH1A1KDM4EMEN1 | |
| SCHEMBL10097356 | 0.78 | ALDH1A1 (0.53) | DYRK1AMAOAMAOBNPSR1IMPDH2 | |
| SCHEMBL16382889 | 0.78 | DYRK1A (0.49) | CYP19A1DYRK1APDE9AMAOAMAOB | |
| SCHEMBL28842633 | 0.78 | DYRK1A (0.46) | CYP19A1DYRK1APDE9AMAOAMAOB | |
| SCHEMBL25929859 | 0.78 | PDE9A (0.47) | CYP19A1DYRK1APDE9APDE1CIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106631982-A | Method for synthesizing amino-substituted carbazole compound | 河南师范大学 | 2017-05-10 | — | — | CN | disclosed |
| WO-2017031276-A1 | METHODS OF PROVIDING NEUROPROTECTIVE THERAPY RELATED TO ADMINISTERING AN ESTROGEN RECEPTOR BETA LIGAND | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-02-23 | — | — | WO | disclosed |
| EP-1829872-B1 | PROCESSES FOR PRODUCTION OF INDOLE COMPOUNDS | NISSAN CHEMICAL IND LTD (JP) | 2015-07-29 | — | — | EP | disclosed |
| EP-1829872-A1 | PROCESSES FOR PRODUCTION OF INDOLE COMPOUNDS | Nissan Chemical Industries, Ltd. (JP) | 2007-09-05 | — | — | EP | disclosed |