Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.38 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.38 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.38 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.38 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.38 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.38 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.38 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5205398 | 0.94 | TSPO (0.44) | TSPOKMT2AMEN1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL5205308 | 0.93 | TPSAB1 (0.38) | TSPOKMT2APSMB8PSMB5MEN1 | |
| Trifluoroacetic Acid SCHEMBL5204269 | 0.92 | KMT2A (0.43) | TSPOKMT2ALMNAMEN1HPGD | |
| Trifluoroacetic Acid SCHEMBL5202690 | 0.92 | ALDH1A1 (0.41) | TSPOPKMKMT2ALMNAMEN1 | |
| Trifluoroacetic Acid SCHEMBL5205606 | 0.91 | TSPO (0.38) | TSPOKMT2APSMB8PSMB5MEN1 | |
| Trifluoroacetic Acid SCHEMBL5208616 | 0.90 | TSPO (0.38) | TSPOKMT2APSMB8PSMB5MEN1 | |
| Trifluoroacetic Acid SCHEMBL5208391 | 0.89 | HCRTR2 (0.39) | TSPOKMT2ALMNAALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5202242 | 0.89 | TPSAB1 (0.37) | TSPOCYP2D6KMT2APSMB8PSMB5 | |
| Trifluoroacetic Acid SCHEMBL5202609 | 0.89 | TSPO (0.44) | TSPOKMT2AMEN1ATMALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5205692 | 0.89 | TSPO (0.39) | TSPOKMT2ALMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |