Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 16/20 | 0.65 |
| ▸ | CCNB1 | P14635 | 16/20 | 0.65 |
| ▸ | CCNA2 | P20248 | 15/20 | 0.65 |
| ▸ | CDK2 | P24941 | 15/20 | 0.65 |
| ▸ | CCNA1 | P78396 | 15/20 | 0.65 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.61 |
| ▸ | MGMT | P16455 | 7/20 | 0.58 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylguanine SCHEMBL231097 | 0.83 | CDK1 (0.69) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| Methylguanine SCHEMBL29903462 | 0.83 | CDK1 (0.69) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL6901880 | 0.81 | CDK1 (0.43) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL8619367 | 0.81 | CDK1 (0.66) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL30176198 | 0.80 | CDK1 (0.77) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL18702352 | 0.80 | CDK1 (0.42) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL8618498 | 0.80 | CDK1 (0.77) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL9682498 | 0.79 | CDK1 (1.00) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL6925968 | 0.78 | CDK1 (0.74) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL8971208 | 0.78 | CDK1 (1.00) | CDK1CCNB1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819718-A1 | DIFLUORONUCLEOSIDES AND PROCESS FOR PREPARATION THEREOF | Sicor Inc. (US) | 2007-08-22 | — | — | EP | claimed |
| US-20060173174-A1 | Difluoronucleosides and process for preparation thereof | SICOR, INC. | 2006-08-03 | — | — | US | claimed |
| WO-2006063105-A1 | DIFLUORONUCLEOSIDES AND PROCESS FOR PREPARATION THEREOF | SICOR INC. (US) | 2006-06-15 | — | — | WO | claimed |
| EP-1819718-A1 | DIFLUORONUCLEOSIDES AND PROCESS FOR PREPARATION THEREOF | Sicor Inc. (US) | 2007-08-22 | — | — | EP | disclosed |
| US-20060173174-A1 | Difluoronucleosides and process for preparation thereof | SICOR, INC. | 2006-08-03 | — | — | US | disclosed |
| WO-2006063105-A1 | DIFLUORONUCLEOSIDES AND PROCESS FOR PREPARATION THEREOF | SICOR INC. (US) | 2006-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173174-A1 | Difluoronucleosides and process for preparation thereof | DUT, NUDT1, DPYD | CDK1 3068/4885CCNB1 2463/4885CCNA2 1443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.