Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.37 |
| ▸ | QPCT | Q16769 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.34 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.33 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201002 | 0.81 | QPCT (0.41) | CYP19A1CYP11B1CYP11B2QPCTCYP3A4 | |
| SCHEMBL5964466 | 0.74 | MAPT (0.44) | HRH4LMNAMAPTMOGAT2USP28 | |
| Hydrochloric Acid SCHEMBL6766934 | 0.72 | CYP2B6 (0.46) | CYP19A1CYP11B1CYP11B2LMNAMAPT | |
| SCHEMBL5964548 | 0.70 | GFER (0.39) | HRH4MAPTMOGAT2USP28USP25 | |
| SCHEMBL6764157 | 0.70 | MAPT (0.41) | HRH4LMNAMAPTMOGAT2USP28 | |
| SCHEMBL5924898 | 0.69 | HRH4 (0.47) | HRH4MAPTUSP28USP25 | |
| SCHEMBL5202386 | 0.68 | MAOA (0.52) | CYP19A1QPCTMAPT | |
| SCHEMBL15244613 | 0.68 | GFER (0.44) | LMNAMAPT | |
| SCHEMBL5200511 | 0.67 | MAPT (0.45) | CYP19A1CYP11B1CYP11B2CYP3A4LMNA | |
| SCHEMBL2636071 | 0.66 | HRH4 (0.54) | HRH4MCHR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1378230-B1 | Para-phenylenediamine derivatives comprising a pyrrolidinyl group substituted by a cyclic radical and their use in colouring keratinic fibres | OREAL (FR) | 2007-11-14 | — | — | EP | claimed |
| US-7132534-B2 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | L'OREAL (FR) | 2006-11-07 | — | — | US | claimed |
| US-20040077852-A1 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | L'OREAL S.A. (FR) | 2004-04-22 | — | — | US | claimed |
| EP-1378230-A1 | Para-phenylenediamine derivatives comprising a pyrrolidinyl group substituted by a cyclic radical and their use in colouring keratinic fibres | L'OREAL (FR) | 2004-01-07 | — | — | EP | claimed |
| US-20040077852-A1 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | L'OREAL S.A. (FR) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077852-A1 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | KRT18, CDC73, VIM | CYP19A1 4095/4885CYP11B1 4287/4885CYP11B2 4272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.