Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | SOD1 | P00441 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202386 | 0.85 | MAOA (0.52) | QPCTCYP19A1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5201853 | 0.81 | CYP19A1 (0.42) | QPCTCYP11B1CYP11B2CYP19A1CYP3A4 | |
| SCHEMBL5964466 | 0.80 | MAPT (0.44) | GAASMN1; SMN2NPC1ALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL6495375 | 0.78 | KDM4E (0.32) | GAASMN1; SMN2NPC1ALOX15HSD17B10 | |
| SCHEMBL2928440 | 0.77 | MAPT (0.33) | GAASMN1; SMN2NPC1ALOX15HSD17B10 | |
| SCHEMBL5924898 | 0.76 | HRH4 (0.47) | GAASMN1; SMN2MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL6766934 | 0.75 | CYP2B6 (0.46) | CYP11B1CYP11B2CYP19A1LMNAMAPT | |
| SCHEMBL19926008 | 0.73 | TBXAS1 (0.50) | GAACYP11B1CYP11B2SMN1; SMN2TBXAS1 | |
| SCHEMBL2539814 | 0.72 | SOD1 (0.57) | QPCTCYP11B1CYP11B2SOD1CYP19A1 | |
| SCHEMBL4954773 | 0.72 | QPCT (0.46) | QPCTGAASOD1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1378230-B1 | Para-phenylenediamine derivatives comprising a pyrrolidinyl group substituted by a cyclic radical and their use in colouring keratinic fibres | OREAL (FR) | 2007-11-14 | — | — | EP | claimed |
| US-7132534-B2 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | L'OREAL (FR) | 2006-11-07 | — | — | US | claimed |
| US-20040077852-A1 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | L'OREAL S.A. (FR) | 2004-04-22 | — | — | US | claimed |
| EP-1378230-A1 | Para-phenylenediamine derivatives comprising a pyrrolidinyl group substituted by a cyclic radical and their use in colouring keratinic fibres | L'OREAL (FR) | 2004-01-07 | — | — | EP | claimed |
| EP-1378230-B1 | Para-phenylenediamine derivatives comprising a pyrrolidinyl group substituted by a cyclic radical and their use in colouring keratinic fibres | OREAL (FR) | 2007-11-14 | — | — | EP | disclosed |
| EP-1378230-B1 | Para-phenylenediamine derivatives comprising a pyrrolidinyl group substituted by a cyclic radical and their use in colouring keratinic fibres | OREAL (FR) | 2007-11-14 | — | — | EP | disclosed |
| US-7132534-B2 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | L'OREAL (FR) | 2006-11-07 | — | — | US | disclosed |
| US-20040077852-A1 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | L'OREAL S.A. (FR) | 2004-04-22 | — | — | US | disclosed |
| EP-1378230-A1 | Para-phenylenediamine derivatives comprising a pyrrolidinyl group substituted by a cyclic radical and their use in colouring keratinic fibres | L'OREAL (FR) | 2004-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077852-A1 | Para-phenylenediamine derivatives containing a pyrrolidyl group, and use of these derivatives for coloring keratin fibers | KRT18, CDC73, VIM | QPCT 2062/4885GAA 4385/4885CYP11B1 4287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.