Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28278049 | 0.90 | SPR (0.30) | — | |
| SCHEMBL15888817 | 0.67 | HDAC8 (0.30) | HDAC8HSP90AA1 | |
| SCHEMBL27889695 | 0.67 | TDP1 (0.31) | HDAC8HSP90AA1 | |
| SCHEMBL16597568 | 0.67 | GRIN1 (0.31) | HDAC8HSP90AA1 | |
| SCHEMBL28079957 | 0.67 | OPRM1 (0.36) | HDAC8HSP90AA1 | |
| SCHEMBL9292272 | 0.65 | GRIN1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL667557 | 0.65 | HSP90AA1 (0.35) | HSP90AA1 | |
| SCHEMBL23216476 | 0.63 | HRH3 (0.38) | — | |
| SCHEMBL28070877 | 0.63 | HDAC8 (0.33) | HDAC8 | |
| SCHEMBL19385802 | 0.63 | PARP1 (0.36) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778673-A1 | NOVEL HYDANTOIN DERIVATIVES FOR THE TREATMENT OF OBSTRUCTIVE AIRWAY DISEASES | AstraZeneca AB (SE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006004532-A1 | NOVEL HYDANTOIN DERIVATIVES FOR THE TREATMENT OF OBSTRUCTIVE AIRWAY DISEASES | ASTRAZENECA AB (SE) | 2006-01-12 | — | — | WO | disclosed |