Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6157615 | 0.78 | GRIN2B (0.48) | GLAHPGDKMT2ATDP1L3MBTL1 | |
| SCHEMBL784586 | 0.77 | GLA (0.62) | GLAHPGDKMT2ANPSR1MRGPRX4 | |
| SCHEMBL1722652 | 0.75 | TDP1 (0.58) | GLAKMT2ANPSR1TDP1L3MBTL1 | |
| SCHEMBL2310275 | 0.74 | LMNA (0.59) | GLAHPGDKMT2AMRGPRX4GAA | |
| SCHEMBL4456238 | 0.73 | GLA (0.65) | GLAHPGDKMT2AMRGPRX4GAA | |
| SCHEMBL6158006 | 0.72 | KMT2A (0.41) | GLAHPGDKMT2ANPSR1TDP1 | |
| SCHEMBL6158003 | 0.72 | KMT2A (0.41) | GLAHPGDKMT2ANPSR1TDP1 | |
| SCHEMBL5422033 | 0.71 | GRIN2B (0.49) | MAPT | |
| SCHEMBL5200890 | 0.71 | GLA (0.47) | GLAHPGDKMT2ANPSR1MRGPRX4 | |
| SCHEMBL3208283 | 0.70 | TDP1 (0.59) | GLAKMT2ANPSR1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056723-B1 | 2-PYRIDYLMETHYLAMINE DERIVATIVES USEFUL AS FUNGICIDES | BAYER CROPSCIENCE LTD (GB) | 2007-11-28 | — | — | EP | disclosed |
| US-6828441-B2 | Agriculture | AVENTIS CROPSCIENCE UK LIMITED (GB) | 2004-12-07 | — | — | US | disclosed |
| CN-1132816-C | 2-pyridylmethylamine derivatives useful as fungicides | AVENTIS CROPSCIENCE UK LTD. (GB) | 2003-12-31 | — | — | CN | disclosed |
| US-20030171410-A1 | 2-pyridylmethylamine derivatives useful as fungicides | AVENTIS CROPSCIENCE UK LIMITED | 2003-09-11 | — | — | US | disclosed |
| US-6503933-B1 | Combating phytopathogenic fungi | AVENTIS CROPSCIENCE UK LIMITED (GB) | 2003-01-07 | — | — | US | disclosed |
| CN-1291187-A | 2-pyridylmethylamine derivatives useful as fungicides | AGREVO UK LTD (GB) | 2001-04-11 | — | — | CN | disclosed |
| EP-1056723-A1 | 2-PYRIDYLMETHYLAMINE DERIVATIVES USEFUL AS FUNGICIDES | Aventis CropScience UK Limited (GB) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999042447-A1 | 2-PYRIDYLMETHYLAMINE DERIVATIVES USEFUL AS FUNGICIDES | AVENTIS CROPSCIENCE UK LIMITED (GB) | 1999-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171410-A1 | 2-pyridylmethylamine derivatives useful as fungicides | PNPO, ME1, CYP2S1 | GLA 2862/4885HPGD 2280/4885KMT2A 407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.