Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 20/20 | 0.45 |
| ▸ | GABRD | O14764 | 20/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 20/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 20/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 20/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 20/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 20/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 20/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 20/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 20/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 20/20 | 0.45 |
| ▸ | GABRE | P78334 | 20/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 20/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 20/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 20/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 20/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25897 | 0.93 | GABRP (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7673514 | 0.89 | GABRP (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7030324 | 0.88 | GABRP (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7250513 | 0.86 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7250518 | 0.86 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8855400 | 0.85 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7673521 | 0.84 | GABRP (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL20089290 | 0.83 | GABRP (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28310778 | 0.81 | GABRB3 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5203598 | 0.81 | GABRP (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948486-B1 | PESTICIDAL 1-ARYLPYRAZOLES | MERIAL LTD (GB) | 2007-11-28 | — | — | EP | claimed |
| EP-0948486-A1 | PESTICIDAL 1-ARYLPYRAZOLES | RHONE-POULENC AGROCHIMIE (FR) | 1999-10-13 | — | — | EP | claimed |
| WO-1998028277-A1 | PESTICIDAL 1-ARYLPYRAZOLES | RHONE-POULENC AGROCHIMIE (FR) | 1998-07-02 | — | — | WO | claimed |
| EP-0948486-B1 | PESTICIDAL 1-ARYLPYRAZOLES | MERIAL LTD (GB) | 2007-11-28 | — | — | EP | disclosed |
| US-6403628-B1 | APHIDICIDE WITH REDUCED TOXICITY TO MAMMALS | RHONE-POULENC AGRO (FR) | 2002-06-11 | — | — | US | disclosed |
| US-6087387-A | 3-ACETYL-1-PHENYL-PYRAZOLE DERIVATIVES INSECTICIDE USEFUL IN THE CONTROL OF INSECTS, NEMATODES OR HELMINTHS | RHONE-POULENC AGRO (FR) | 2000-07-11 | — | — | US | disclosed |
| EP-0948486-A1 | PESTICIDAL 1-ARYLPYRAZOLES | RHONE-POULENC AGROCHIMIE (FR) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998028277-A1 | PESTICIDAL 1-ARYLPYRAZOLES | RHONE-POULENC AGROCHIMIE (FR) | 1998-07-02 | — | — | WO | disclosed |