Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | SDCBP | O00560 | 1/20 | 0.37 |
| ▸ | SDC2 | P34741 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.35 |
| ▸ | GNA15 | P30679 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5208000 | 0.92 | HDAC1 (0.44) | HDAC1SDCBPSDC2FFAR1GNA15 | |
| SCHEMBL5205381 | 0.92 | HDAC1 (0.41) | HDAC1SDCBPSDC2PPARGPPARD | |
| SCHEMBL5206214 | 0.89 | ALDH1A1 (0.40) | HDAC1SDCBPSDC2LTB4R2NQO2 | |
| SCHEMBL5205377 | 0.89 | PPARG (0.40) | HDAC1PPARGPPARDPPARAGLS | |
| SCHEMBL5208677 | 0.84 | NR3C1 (0.41) | HDAC1SUCNR1NR3C1 | |
| SCHEMBL5204889 | 0.83 | HDAC1 (0.47) | HDAC1SDCBPSDC2LTB4R2AKT1 | |
| SCHEMBL5208124 | 0.82 | PPARG (0.40) | PPARGPPARDPPARA | |
| SCHEMBL5203418 | 0.81 | ALDH1A1 (0.40) | HDAC1SDCBPSDC2PPARGPPARD | |
| SCHEMBL5204311 | 0.81 | ALDH1A1 (0.42) | HDAC1SDCBPSDC2TDP1 | |
| SCHEMBL5203510 | 0.81 | PPARG (0.39) | PPARGPPARDPPARAGLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |
| EP-1123918-B1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | TAKEDA PHARMACEUTICAL (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1123918-A1 | AROMATIC AMINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |