Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | SDCBP | O00560 | 1/20 | 0.41 |
| ▸ | SDC2 | P34741 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5208000 | 0.91 | HDAC1 (0.44) | HDAC1SDCBPSDC2TSPOAKT1 | |
| SCHEMBL5206192 | 0.88 | HDAC1 (0.40) | HDAC1SDCBPSDC2TSPOALDH1A1 | |
| SCHEMBL5202825 | 0.83 | HDAC1 (0.44) | HDAC1SDCBPSDC2LTB4R2CTSS | |
| SCHEMBL5205381 | 0.83 | HDAC1 (0.41) | HDAC1SDCBPSDC2TSPO | |
| SCHEMBL5204311 | 0.80 | ALDH1A1 (0.42) | HDAC1SDCBPSDC2TSPOALDH1A1 | |
| SCHEMBL5204997 | 0.78 | ALDH1A1 (0.43) | HDAC1TSPOALDH1A1RAB9ACTSS | |
| SCHEMBL5202464 | 0.78 | ALDH1A1 (0.41) | HDAC1TSPOALDH1A1 | |
| SCHEMBL5208677 | 0.77 | NR3C1 (0.41) | HDAC1TSPOALDH1A1KMT2A | |
| SCHEMBL7242557 | 0.76 | HDAC1 (0.50) | HDAC1SDCBPSDC2NAMPTCTSS | |
| SCHEMBL1691047 | 0.76 | HDAC1 (0.67) | HDAC1SDCBPSDC2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |