SCHEMBL842957

SCHEMBL842957

Cc1ccc(-c2c(C)n[nH]c2N)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.47
AKT2 P31751 2/20 0.46
CHEK1 O14757 1/20 0.46
NPC1 O15118 1/20 0.42
GAA P10253 1/20 0.42
IKBKB O14920 2/20 0.41
MAP3K14 Q99558 1/20 0.41
CHUK O15111 1/20 0.41
LMNA P02545 4/20 0.40
ALDH1A1 P00352 1/20 0.40
PIK3CD O00329 1/20 0.39
PIK3CA P42336 1/20 0.39
PIK3CB P42338 1/20 0.39
PIK3CG P48736 1/20 0.39
PRKDC P78527 1/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
HEXA P06865 1/20 0.39
HEXB P07686 1/20 0.39
NFKB1 P19838 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13310491 0.85 IKBKB (0.59) SMN1; SMN2AKT2CHEK1NPC1GAA
SCHEMBL758310 0.85 MAPK14 (0.45) AKT2CHEK1NPC1IKBKBMAP3K14
SCHEMBL1248139 0.85 IKBKB (0.59) SMN1; SMN2AKT2CHEK1GAAIKBKB
SCHEMBL1057636 0.84 AKT2 (0.66) SMN1; SMN2AKT2CHEK1NPC1LMNA
SCHEMBL13516427 0.82 MAPT (0.50) SMN1; SMN2NPC1GAAALDH1A1KMT2A
SCHEMBL27926884 0.82 AKT2 (0.46) AKT2CHEK1IKBKBMAP3K14CHUK
SCHEMBL10275234 0.80 KIF11 (0.44) AKT2CHEK1NPC1GAAIKBKB
SCHEMBL21262737 0.79 AKT2 (0.70) SMN1; SMN2AKT2CHEK1IKBKBMAP3K14
SCHEMBL4412336 0.78 SMN1; SMN2 (0.42) SMN1; SMN2AKT2NPC1GAAIKBKB
SCHEMBL15020946 0.78 HEXA (0.53) SMN1; SMN2NPC1GAAIKBKBMAP3K14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025106697-A1 BIO-BASED COMPOSITIONS FOR PHOTORESISTS AND PATTERNING HUSTAD PHILLIP DENE (US) 2025-05-22 WO disclosed
WO-2024107979-A1 BIO-BASED SOLVENTS FOR NEGATIVE TONE DEVELOPMENT HUSTAD PHILLIP DENE (US) 2024-05-23 WO disclosed
US-8975264-B2 Compound acting as a cannabinoid receptor-1 inhibitor AMOREPACIFIC CORPORATION (KR) 2015-03-10 US disclosed
WO-2014030723-A1 PATTERN FORMING METHOD, ELECTRON BEAM-SENSITIVE OR EXTREME ULTRAVIOLET RAY-SENSITIVE RESIN COMPOSITION, RESIST FILM, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2014-02-27 WO disclosed
WO-2013147325-A1 PATTERN FORMING METHOD, METHOD FOR SELECTING HEATING TEMPERATURE IN PATTERN FORMING METHOD, EXTREME ULTRAVIOLET-SENSITIVE RESIN COMPOSITION, RESIST FILM, MANUFACTURING METHOD OF ELECTRONIC DEVICE USING THE SAME, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2013-10-03 WO disclosed
WO-2013141395-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE COMPOSITION, RESIST FILM USING THE SAME, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2013-09-26 WO disclosed
EP-2617723-A2 NOVEL COMPOUND ACTING AS A CANNABINOID RECEPTOR-1 INHIBITOR Amorepacific Corporation (KR) 2013-07-24 EP disclosed
WO-2013100158-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM AND PATTERN FORMING METHOD, EACH USING THE SAME FUJIFILM CORPORATION (JP) 2013-07-04 WO disclosed
US-20130158025-A1 NOVEL COMPOUND ACTING AS A CANNABINOID RECEPTOR-1 INHIBITOR AMOREPACIFIC CORPORATION (KR) 2013-06-20 US disclosed
WO-2013047902-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC-RAY- OR RADIATION-SENSITIVE FILM THEREFROM AND METHOD OF FORMING PATTERN FUJIFILM CORPORATION (JP) 2013-04-04 WO disclosed
EP-2387735-A1 NONPOLYMERIC BINDERS FOR SEMICONDUCTOR SUBSTRATE COATINGS FujiFilm Electronic Materials USA, Inc. (US) 2011-11-23 EP disclosed
US-8037621-B2 Article of footwear including a woven strap system NIKE, INC. (US) 2011-10-18 US disclosed
WO-2011096552-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR MANUFACTURING STRUCTURAL BODY, AND LIQUID DISCHARGE HEAD CANON KABUSHIKI KAISHA (JP) 2011-08-11 WO disclosed
EP-2296040-A1 Positive photosensitive composition Fujifilm Corporation (JP) 2011-03-16 EP disclosed
WO-2011014520-A2 COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY IRM LLC (BM) 2011-02-03 WO disclosed
EP-2260352-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN THEREWITH FUJIFILM Corporation (JP) 2010-12-15 EP disclosed
WO-2010083350-A1 NONPOLYMERIC BINDERS FOR SEMICONDUCTOR SUBSTRATE COATINGS FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2010-07-22 WO disclosed
WO-2009123341-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION AND METHOD OF FORMING PATTERN THEREWITH FUJIFILM CORPORATION (JP) 2009-10-08 WO disclosed
US-20030010748-A1 Positive photosensitive compositions FUJI PHOTO FILM CO., LTD. 2003-01-16 US disclosed
US-6291130-B1 Positive photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 2001-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130158025-A1 NOVEL COMPOUND ACTING AS A CANNABINOID RECEPTOR-1 INHIBITOR CNR1, CNR2, GPR18 SMN1; SMN2 4424/4885AKT2 2803/4885CHEK1 3449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.