Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 5/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29112760 | 0.83 | PIM1 (0.60) | MTNR1AMTNR1BMEN1KMT2APIM1 | |
| SCHEMBL5203500 | 0.82 | MTNR1A (0.46) | MTNR1AMTNR1BPARP1HTR3AHSD17B10 | |
| SCHEMBL10768300 | 0.77 | MEN1 (0.52) | MEN1KMT2APIM1PARP1KDM4E | |
| SCHEMBL5203518 | 0.77 | KMT2A (0.41) | MEN1KMT2AHTR3ANCF1KDM4E | |
| SCHEMBL3577364 | 0.77 | MCHR1 (0.49) | MTNR1AMTNR1BHTR3AMCHR1 | |
| SCHEMBL2670940 | 0.76 | PIM1 (0.47) | KMT2APIM1PARP1HTR3APLAU | |
| SCHEMBL4823327 | 0.75 | PIM1 (0.69) | KMT2APIM1PARP1HTR3APLAU | |
| SCHEMBL2316635 | 0.75 | MGAM (0.47) | MEN1KMT2ANCF1KDM4EMAPT | |
| SCHEMBL31140011 | 0.75 | MGAM (0.47) | MEN1KMT2ANCF1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL3583982 | 0.75 | MCHR1 (0.47) | MTNR1AMTNR1BHTR3AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492771-B1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AG (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1492771-A1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082827-A1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-09 | — | — | WO | disclosed |