Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202897 | 0.82 | MTNR1A (0.42) | MTNR1AMTNR1BHTR3AMCHR1HSD17B10 | |
| SCHEMBL3577364 | 0.80 | MCHR1 (0.49) | MTNR1AMTNR1BHTR3AMCHR1PDE10A | |
| SCHEMBL5206188 | 0.79 | HTR3A (0.40) | HTR3AALDH1A1CFTRHSD17B10 | |
| Hydrochloric Acid SCHEMBL3583982 | 0.78 | MCHR1 (0.47) | MTNR1AMTNR1BHTR3AMCHR1PDE10A | |
| SCHEMBL6225917 | 0.77 | KDM4E (0.48) | MTNR1AMTNR1BALDH1A1HSD17B10 | |
| SCHEMBL4707883 | 0.77 | XIAP (0.45) | MTNR1AMTNR1BMCHR1ALDH1A1CFTR | |
| SCHEMBL4819927 | 0.76 | ALDH1A1 (0.46) | ALDH1A1CFTRHSD17B10 | |
| SCHEMBL6223869 | 0.73 | KDM4E (0.44) | MTNR1AMTNR1BALDH1A1HSD17B10 | |
| SCHEMBL11817511 | 0.71 | KDM4E (0.56) | MTNR1AMTNR1BALDH1A1HSD17B10 | |
| SCHEMBL4710517 | 0.71 | HSD17B10 (0.33) | MTNR1AMTNR1BHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492771-B1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AG (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1492771-A1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082827-A1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-09 | — | — | WO | disclosed |