Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | STAT1 | P42224 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200499 | 0.79 | KDM4E (0.37) | KDM4EALDH1A1LMNAHSD17B10MAPT | |
| SCHEMBL6837756 | 0.76 | ALDH1A1 (0.43) | KDM4EKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL5201408 | 0.74 | TXNRD1 (0.45) | KDM4EKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL8951994 | 0.74 | KDM4C (0.41) | KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL4824144 | 0.73 | SMN1; SMN2 (0.40) | KDM4EKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL31321811 | 0.70 | AOC3 (0.38) | KDM4EKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL3828975 | 0.70 | NCEH1 (0.37) | ALDH1A1LMNACYP1A2NPC1RAB9A | |
| SCHEMBL4823719 | 0.69 | TARBP2 (0.41) | KDM4EKMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL28524665 | 0.68 | ALDH1A1 (0.51) | KDM4EALDH1A1LMNAHSD17B10AOC3 | |
| SCHEMBL15688428 | 0.67 | AOC3 (0.37) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492771-B1 | QUINOLINE AND ISOQUINOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AG (DE) | 2007-02-28 | — | — | EP | disclosed |