Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | AHCY | P23526 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MASP2 | O00187 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203498 | 0.91 | TSPO (0.39) | TSPOAHCYPTGER4PTGER2PKM | |
| SCHEMBL5203488 | 0.91 | TSPO (0.39) | TSPOAHCYPTGER4PTGER2PKM | |
| Hydrochloric Acid SCHEMBL5202593 | 0.88 | TSPO (0.40) | TSPOAHCYPTGER4PTGER2PKM | |
| SCHEMBL5203387 | 0.88 | TSPO (0.38) | TSPOAHCYIDH1PTGER4PTGER2 | |
| SCHEMBL5205622 | 0.85 | PPARG (0.36) | TSPOAHCYPKMMAPK1RAB9A | |
| SCHEMBL5203396 | 0.85 | TSPO (0.35) | TSPOAHCYIDH1PKMMAPK1 | |
| SCHEMBL7845763 | 0.83 | TSPO (0.39) | TSPOAHCYPKMMAPK1RAB9A | |
| Hydrochloric Acid SCHEMBL5204956 | 0.83 | PTGES (0.37) | TSPOAHCYPKMMAPK1RAB9A | |
| Hydrochloric Acid SCHEMBL5208593 | 0.79 | PTGES (0.38) | TSPOAHCYPKMMAPK1RAB9A | |
| SCHEMBL5205540 | 0.78 | P2RX4 (0.37) | TSPOAHCYP2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160887-B1 | Aromatic amine derivatives, their production and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-09 | — | — | US | disclosed |