Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6339479 | 0.81 | MAPT (0.37) | CYP2C9CYP1A2ALDH1A1MAPTMEN1 | |
| SCHEMBL5205549 | 0.80 | HTR2A (0.49) | CYP1A2ALDH1A1MAPTKDM4ECYP2C19 | |
| SCHEMBL5203576 | 0.78 | TNFRSF1A (0.45) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL5208220 | 0.78 | SMN1; SMN2 (0.48) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL5207796 | 0.77 | CYP3A4 (0.52) | CYP1A2MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL5203586 | 0.75 | MAPT (0.40) | CYP2C9CYP1A2ALDH1A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL5205490 | 0.73 | MAPT (0.52) | CYP2C9CYP1A2ALDH1A1MAPTMEN1 | |
| SCHEMBL5205202 | 0.73 | TPMT (0.54) | ALDH1A1MEN1KMT2AHSD17B10L3MBTL1 | |
| SCHEMBL5203822 | 0.73 | GAA (0.48) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL5205439 | 0.73 | TNFRSF1A (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403251-B1 | BIS(2-ARYL-5-PYRIDYL) DERIVATIVE | KOWA CO (JP) | 2007-07-18 | — | — | EP | disclosed |
| EP-1403251-A1 | BIS(2-ARYL-5-PYRIDYL) DERIVATIVE | Kowa Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |