SCHEMBL5207796

SCHEMBL5207796

COc1cc(OB(O)O)cc(OC)c1OC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.52
MAPT P10636 1/20 0.52
ACHE P22303 1/20 0.48
CA9 Q16790 1/20 0.46
TUBB4A P04350 7/20 0.46
TUBB P07437 7/20 0.46
TUBA3C P0DPH7 7/20 0.46
TUBA1B P68363 7/20 0.46
TUBA4A P68366 7/20 0.46
TUBB4B P68371 7/20 0.46
TUBB3 Q13509 7/20 0.46
TUBB2A Q13885 7/20 0.46
TUBB8 Q3ZCM7 7/20 0.46
TUBA3E Q6PEY2 7/20 0.46
TUBA1A Q71U36 7/20 0.46
TUBA1C Q9BQE3 7/20 0.46
TUBB6 Q9BUF5 7/20 0.46
TUBB2B Q9BVA1 7/20 0.46
TUBB1 Q9H4B7 7/20 0.46
PTGS2 P35354 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5203651 0.88 CYP1A2 (0.48) CYP3A4MAPTACHECA9TUBB4A
SCHEMBL5231515 0.83 MAPT (0.35) CYP3A4MAPTACHETUBB4ATUBB
SCHEMBL5206243 0.83 GAA (0.38) CYP3A4MAPTACHETUBB4ATUBB
SCHEMBL5205549 0.83 HTR2A (0.49) MAPTTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL5203371 0.83 CYP1A2 (0.43) CYP3A4MAPTACHECA9TUBB4A
SCHEMBL6628469 0.83 RXFP1 (0.39) CYP3A4MAPTACHECA9PTGS2
SCHEMBL5206042 0.81 CA12 (0.35) CYP3A4MAPTCA9TUBB4ATUBB
SCHEMBL5206460 0.81 CA12 (0.35) CYP3A4MAPTCA9TUBB4ATUBB
SCHEMBL5208220 0.80 SMN1; SMN2 (0.48) MAPTTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL5203576 0.80 TNFRSF1A (0.45) CYP3A4MAPTTUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119192215-A Suzuki coupling method of B (9, 10) o-dibromo-substituted m-carborane and application thereof 华东理工大学 2024-12-27 CN claimed
CN-103804196-B Star-shaped adamantane derivative molecular glass and preparation method and application thereof 中国科学院理化技术研究所 2016-08-31 CN claimed
CN-122036736-A Pyrrolo [2,3-d ] pyrimidine derivative, synthetic method and application 云南大学 2026-05-15 CN disclosed
CN-119192215-A Suzuki coupling method of B (9, 10) o-dibromo-substituted m-carborane and application thereof 华东理工大学 2024-12-27 CN disclosed
CN-114573490-B Diaryl-2H-aziridine compounds, preparation method and application thereof 复旦大学 2024-04-30 CN disclosed
CN-110015952-B Diaryl methane compound and preparation method and application thereof 北京大学深圳研究生院 2022-08-19 CN disclosed
CN-104114558-B Furopyridine derivant 默克专利股份公司 2016-10-26 CN disclosed
CN-105998028-A Hydroxylamine compounds and methods of their use 科尔比制药公司 2016-10-12 CN disclosed
CN-103804196-B Star-shaped adamantane derivative molecular glass and preparation method and application thereof 中国科学院理化技术研究所 2016-08-31 CN disclosed
CN-104803826-B A kind of method utilizing hexafluoropropene that aryl boric acid directly aoxidizes seven fluorine isopropylations 中国科学院上海有机化学研究所 2016-08-17 CN disclosed
CN-105693610-A A preparing method of (R,S)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, a lorcaserin intermediate 四川省宜宾五粮液集团宜宾制药有限责任公司 2016-06-22 CN disclosed
CN-100522910-C Fluorocombretastatin and derivatives thereof SIGMA TAU IND FARMACEUTI (IT) 2009-08-05 CN disclosed
EP-1403250-B1 BIS(5-ARYL-2-PYRIDYL) DERIVATIVE KOWA CO (JP) 2007-07-18 EP disclosed
EP-1403251-B1 BIS(2-ARYL-5-PYRIDYL) DERIVATIVE KOWA CO (JP) 2007-07-18 EP disclosed
CN-1826308-A Fluorocombretastatin and derivatives thereof SIGMA TAU IND FARMACEUTI (IT) 2006-08-30 CN disclosed
EP-1403250-A1 BIS(5-ARYL-2-PYRIDYL) DERIVATIVE Kowa Co., Ltd. (JP) 2004-03-31 EP disclosed
EP-1403251-A1 BIS(2-ARYL-5-PYRIDYL) DERIVATIVE Kowa Co., Ltd. (JP) 2004-03-31 EP disclosed