Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5208220 | 0.87 | SMN1; SMN2 (0.48) | MAPK1SMN1; SMN2MAPTL3MBTL1RAB9A | |
| SCHEMBL5205549 | 0.83 | HTR2A (0.49) | SMN1; SMN2MAPTALDH1A1LMNATUBB4A | |
| SCHEMBL5205311 | 0.80 | MAPK1 (0.35) | TNFRSF1AMAPK1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL5207796 | 0.80 | CYP3A4 (0.52) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6340052 | 0.79 | TNFRSF1A (0.47) | TNFRSF1AMAPK1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL5203497 | 0.78 | CYP2C9 (0.35) | MAPK1MAPTL3MBTL1ALDH1A1TUBB4A | |
| SCHEMBL18292053 | 0.76 | MAPK1 (0.58) | TNFRSF1AMAPK1SMN1; SMN2ALDH1A1TUBB4A | |
| SCHEMBL5203822 | 0.75 | GAA (0.48) | MAPTALDH1A1LMNAHPGDKMT2A | |
| SCHEMBL5205439 | 0.75 | TNFRSF1A (0.51) | TNFRSF1ASMN1; SMN2RAB9ATUBB4ATUBB | |
| SCHEMBL5208622 | 0.73 | TNFRSF1A (0.47) | TNFRSF1AMAPK1SMN1; SMN2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403251-B1 | BIS(2-ARYL-5-PYRIDYL) DERIVATIVE | KOWA CO (JP) | 2007-07-18 | — | — | EP | disclosed |
| EP-1403251-A1 | BIS(2-ARYL-5-PYRIDYL) DERIVATIVE | Kowa Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |