Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203576 | 0.87 | TNFRSF1A (0.45) | SMN1; SMN2ALDH1A1MEN1HPGDHTT | |
| SCHEMBL5205549 | 0.86 | HTR2A (0.49) | SMN1; SMN2ALDH1A1MAPTTUBB4ATUBB | |
| SCHEMBL5207796 | 0.80 | CYP3A4 (0.52) | MEN1KMT2AMAPTTUBB4ATUBB | |
| SCHEMBL6341314 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1MEN1HPGDHTT | |
| SCHEMBL5203497 | 0.78 | CYP2C9 (0.35) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL5205311 | 0.77 | MAPK1 (0.35) | SMN1; SMN2ALDH1A1MEN1HPGDHTT | |
| SCHEMBL5208870 | 0.75 | TSHR (0.49) | SMN1; SMN2ALDH1A1MEN1HTTKMT2A | |
| SCHEMBL5203822 | 0.75 | GAA (0.48) | ALDH1A1MEN1HPGDKMT2AMAPT | |
| SCHEMBL5205439 | 0.75 | TNFRSF1A (0.51) | SMN1; SMN2RAB9ATUBB4ATUBBTUBA3C | |
| SCHEMBL7922019 | 0.75 | MAPT (0.45) | SMN1; SMN2ALDH1A1MEN1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403251-B1 | BIS(2-ARYL-5-PYRIDYL) DERIVATIVE | KOWA CO (JP) | 2007-07-18 | — | — | EP | disclosed |
| EP-1403251-A1 | BIS(2-ARYL-5-PYRIDYL) DERIVATIVE | Kowa Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |