Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1999857 | 0.82 | PDE7A (0.54) | PDE7AALDH1A1POLBHIF1AAR | |
| SCHEMBL3207733 | 0.81 | AR (0.53) | PDE7AALDH1A1POLBARMAPT | |
| SCHEMBL1532376 | 0.79 | FFAR4 (0.60) | PDE7AALDH1A1POLBHIF1ALMNA | |
| Water SCHEMBL27993079 | 0.79 | AR (0.52) | PDE7AALDH1A1POLBARMAPT | |
| SCHEMBL85544 | 0.79 | ALDH1A1 (0.58) | PDE7AALDH1A1POLBHIF1AAR | |
| SCHEMBL4310481 | 0.79 | ALDH1A1 (0.53) | PDE7AALDH1A1POLBHIF1AAR | |
| SCHEMBL3965308 | 0.79 | PDE7A (0.51) | PDE7AALDH1A1POLBHIF1AAR | |
| SCHEMBL31138869 | 0.79 | ALDH1A1 (0.53) | PDE7AALDH1A1POLBHIF1AAR | |
| SCHEMBL14149035 | 0.78 | PDE7A (0.50) | PDE7AALDH1A1POLBHIF1AAR | |
| SCHEMBL1408443 | 0.78 | PDE7A (0.50) | PDE7AALDH1A1POLBHIF1AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791809-A1 | SUBSTITUTED ANILINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006029623-A1 | SUBSTITUTED ANILINE DERIVATIVES | H. LUNDBECK A/S (DK) | 2006-03-23 | — | — | WO | disclosed |