Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.72 |
| ▸ | RAB9A | P51151 | 9/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | HPGD | P15428 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12171480 | 0.85 | RAB9A (0.81) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL2681562 | 0.84 | RAB9A (0.93) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL4883318 | 0.84 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL12171404 | 0.84 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL12171414 | 0.82 | NPC1 (0.96) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL12171339 | 0.82 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL12171801 | 0.82 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL12171744 | 0.82 | RAB9A (0.71) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11438341 | 0.82 | NPC1 (0.89) | NPC1RAB9ASMN1; SMN2HPGDKMT2A | |
| SCHEMBL12171792 | 0.81 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223791-B2 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-05-29 | — | — | US | disclosed |
| US-20040157881-A1 | Function regulator for retinoid relative receptor | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-08-12 | — | — | US | disclosed |
| EP-1405636-A1 | FUNCTION REGULATOR FOR RETINOID RELATIVE RECEPTOR | Takeda Chemical Industries, Ltd. (JP) | 2004-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157881-A1 | Function regulator for retinoid relative receptor | RXRA, RARA, RARG | NPC1 828/4885RAB9A 1448/4885SMN1; SMN2 4686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.