SCHEMBL52039

SCHEMBL52039

CC(O)C(Oc1ccc(S(=O)(=O)c2ccc(O)cc2)cc1)Oc1ccc(S(=O)(=O)c2ccc(OC(Oc3ccc(S(=O)(=O)c4ccc(O)cc4)cc3)C(C)O)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.59
GAA P10253 2/20 0.59
ELANE P08246 2/20 0.51
POLB P06746 1/20 0.43
MAPT P10636 1/20 0.43
ENPP2 Q13822 1/20 0.41
RAPGEF4 Q8WZA2 1/20 0.40
LMNA P02545 2/20 0.38
ALDH1A1 P00352 2/20 0.38
ESR1 P03372 1/20 0.37
CA2 P00918 3/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA9 Q16790 1/20 0.37
KMT2A Q03164 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1395595 0.89 PTGS1 (0.48) PKMGAAELANEPOLBMAPT
SCHEMBL1836003 0.89 GAA (0.48) PKMGAAELANELMNAALDH1A1
SCHEMBL26268 0.84 PKM (0.65) PKMGAAELANEPOLBMAPT
SCHEMBL1792957 0.84 PKM (0.65) PKMGAAELANEPOLBMAPT
SCHEMBL1791759 0.84 PKM (0.65) PKMGAAELANEPOLBMAPT
SCHEMBL24178901 0.81 PKM (0.61) PKMGAAELANEPOLBMAPT
SCHEMBL14227005 0.81 PKM (0.66) PKMGAAELANEPOLBMAPT
SCHEMBL1396160 0.80 PKM (0.59) PKMGAAELANEPOLBMAPT
SCHEMBL417296 0.80 PKM (0.59) PKMGAAELANEPOLBMAPT
SCHEMBL1794613 0.80 PKM (0.59) PKMGAAELANEPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3475095-B1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE RICOH CO LTD (JP) 2020-01-22 EP disclosed
US-20190152248-A1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE RICOH COMPANY, LTD. (JP) 2019-05-23 US disclosed
EP-3475095-A1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE Ricoh Company, Ltd. (JP) 2019-05-01 EP disclosed
EP-2484534-B1 RECORDING MATERIAL USING PHENOLIC COMPOUND NIPPON SODA CO (JP) 2019-01-16 EP disclosed
EP-1930318-B1 Process for producing diphenyl sulfone compound NIPPON SODA CO (JP) 2017-03-08 EP disclosed
US-8722576-B2 Thermosensitive recording label NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2014-05-13 US disclosed
EP-2474963-B1 THERMOSENSITIVE RECORDING LABEL JUJO PAPER CO LTD (JP) 2013-11-13 EP disclosed
US-8551911-B2 Recording material using phenolic compound NIPPON SODA CO., LTD. (JP) 2013-10-08 US disclosed
EP-1273570-B1 PROCESS FOR PRODUCING DIPHENYL SULFONE COMPOUND NIPPON SODA CO (JP) 2013-07-17 EP disclosed
US-20120208698-A1 THERMOSENSITIVE RECORDING LABEL NIPPON PAPER INDUSTRIES CO., LTD 2012-08-16 US disclosed
EP-1273570-A1 PROCESS FOR PRODUCING DIPHENYL SULFONE COMPOUND NIPPON SODA CO., LTD. (JP) 2003-01-08 EP disclosed
US-6407036-B1 MIXTURE OF FATTY AMIDE AND DIPHENYL SULFONE COMPOUND NIPPON PAPER INDUSTRIES CO. LTD (JP) 2002-06-18 US disclosed
EP-0860429-B1 DIPHENYL SULFONE CROSSLINKING TYPE COMPOUNDS AND RECORDING MATERIALS USING THEM NIPPON SODA CO (JP) 2001-12-12 EP disclosed
US-6303540-B1 CONTAINING DIPHENYLSULFONE BRIDGEABLE TYPE COMPOUND AND SULFONAMIDE COMPOUND NIPPON PAPER INDUSTRIES CO LTD (JP) 2001-10-16 US disclosed
EP-1092552-A1 THERMAL RECORDING MATERIAL NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2001-04-18 EP disclosed
EP-1092553-A1 THERMAL RECORDING MATERIAL NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2001-04-18 EP disclosed
EP-1092551-A2 Multi chromatic thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2001-04-18 EP disclosed
EP-0999072-A1 A thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-05-10 EP disclosed
US-6037308-A HIGH RECORDED IMAGE PRESERVABILITY NIPPON SODA CO., LTD. (JP) 2000-03-14 US disclosed
EP-0860429-A1 DIPHENYL SULFONE CROSSLINKING TYPE COMPOUNDS AND RECORDING MATERIALS USING THEM NIPPON SODA CO., LTD. (JP) 1998-08-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190152248-A1 THERMOSENSITIVE RECORDING MEDIUM AND ARTICLE CACNA1S, NCS1, TRPA1 PKM 1477/4885GAA 3682/4885ELANE 2435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.