Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5628234 | 0.95 | ALDH1A1 (0.38) | ALDH1A1KDM4ELMNAGPR55MAPT | |
| Trifluoroacetic Acid SCHEMBL5280152 | 0.94 | ALDH1A1 (0.40) | ALDH1A1KDM4ELMNAGPR55MAPT | |
| Trifluoroacetic Acid SCHEMBL5207834 | 0.86 | PDE4D (0.41) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| Trifluoroacetic Acid SCHEMBL5209718 | 0.85 | FLT3 (0.39) | ALDH1A1KDM4ELMNAMAPTRXFP1 | |
| Trifluoroacetic Acid SCHEMBL5211954 | 0.85 | FLT3 (0.37) | ALDH1A1KDM4ELMNAMAPTRXFP1 | |
| Trifluoroacetic Acid SCHEMBL5204002 | 0.85 | FLT3 (0.38) | ALDH1A1KDM4EMAPTRXFP1FLT3 | |
| Trifluoroacetic Acid SCHEMBL5208332 | 0.84 | FLT3 (0.35) | ALDH1A1KDM4ELMNAMAPTRXFP1 | |
| Trifluoroacetic Acid SCHEMBL5207793 | 0.84 | PDE4D (0.40) | ALDH1A1KDM4ELMNAMAPTTLR2 | |
| Trifluoroacetic Acid SCHEMBL5207943 | 0.83 | KIF11 (0.44) | ALDH1A1LMNAMAPTRXFP1FLT3 | |
| Trifluoroacetic Acid SCHEMBL5207372 | 0.83 | RORC (0.47) | MAPTFLT3RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-B1 | SERINE PROTEASE INHIBITORS | TULARIK LTD (GB) | 2007-02-28 | — | — | EP | disclosed |