Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203638 | 0.85 | GAA (0.50) | GAARAD52CHIAF2PRSS1 | |
| SCHEMBL6266805 | 0.85 | GAA (0.70) | GAARAD52F2PRSS1PRSS2 | |
| SCHEMBL5202552 | 0.83 | GFER (0.57) | GAARAD52MAPTALDH1A1GFER | |
| SCHEMBL7032717 | 0.83 | GAA (0.67) | GAARAD52MAPTALDH1A1MAPK1 | |
| SCHEMBL2923577 | 0.80 | GAA (0.67) | GAARAD52MAPTALDH1A1MAPK1 | |
| SCHEMBL6151434 | 0.80 | GAA (0.77) | GAARAD52MAPTALDH1A1GFER | |
| SCHEMBL15358759 | 0.80 | GAA (0.77) | GAARAD52MAPTALDH1A1GFER | |
| SCHEMBL5202379 | 0.79 | CHIA (0.63) | GAARAD52CHIAF2PRSS1 | |
| SCHEMBL6223137 | 0.78 | GAA (0.65) | GAARAD52MAPTALDH1A1MAPK1 | |
| SCHEMBL6273294 | 0.78 | GAA (0.65) | GAARAD52MAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417184-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES CONTAINING A PARAPHENYLENEDIAMINE SUBSTITUTED BY A DIAZACYCLOHEPTANE RADICAL | OREAL (FR) | 2007-08-29 | — | — | EP | claimed |
| US-7241317-B2 | Composition for dyeing keratin fibers comprising at least one para-phenylenediamine substituted with a diazacycloheptane radical | L'OREAL, S.A. (FR) | 2007-07-10 | — | — | US | claimed |
| US-20050102769-A1 | Composition for dyeing keratinous fibers containing a paraphenylenediamine substituted by a diazacycloheptane radical | L'OREAL S.A. (FR) | 2005-05-19 | — | — | US | claimed |
| EP-1417184-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES CONTAINING A PARAPHENYLENEDIAMINE SUBSTITUTED BY A DIAZACYCLOHEPTANE RADICAL | OREAL (FR) | 2007-08-29 | — | — | EP | disclosed |
| EP-1417184-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES CONTAINING A PARAPHENYLENEDIAMINE SUBSTITUTED BY A DIAZACYCLOHEPTANE RADICAL | OREAL (FR) | 2007-08-29 | — | — | EP | disclosed |
| US-7241317-B2 | Composition for dyeing keratin fibers comprising at least one para-phenylenediamine substituted with a diazacycloheptane radical | L'OREAL, S.A. (FR) | 2007-07-10 | — | — | US | disclosed |
| US-7241317-B2 | Composition for dyeing keratin fibers comprising at least one para-phenylenediamine substituted with a diazacycloheptane radical | L'OREAL, S.A. (FR) | 2007-07-10 | — | — | US | disclosed |
| US-7241317-B2 | Composition for dyeing keratin fibers comprising at least one para-phenylenediamine substituted with a diazacycloheptane radical | L'OREAL, S.A. (FR) | 2007-07-10 | — | — | US | disclosed |
| US-20050102769-A1 | Composition for dyeing keratinous fibers containing a paraphenylenediamine substituted by a diazacycloheptane radical | L'OREAL S.A. (FR) | 2005-05-19 | — | — | US | disclosed |
| EP-1417184-A1 | COMPOSITION FOR DYEING KERATINOUS FIBRES CONTAINING A PARAPHENYLENEDIAMINE SUBSTITUTED BY A DIAZACYCLOHEPTANE RADICAL | L'OREAL (FR) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003014093-A1 | COMPOSITION FOR DYEING KERATINOUS FIBRES CONTAINING A PARAPHENYLENEDIAMINE SUBSTITUTED BY A DIAZACYCLOHEPTANE RADICAL | L'OREAL (FR) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050102769-A1 | Composition for dyeing keratinous fibers containing a paraphenylenediamine substituted by a diazacycloheptane radical | KRT18, HPD, PPOX | GAA 4732/4885RAD52 542/4885CHIA 3773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.