Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5343866 | 0.81 | GPR35 (0.48) | BRD4GPR35LMNAACACBACACA | |
| SCHEMBL5268234 | 0.81 | BRD4 (0.44) | BRD4LMNAACACBACACASCN9A | |
| SCHEMBL4022950 | 0.80 | ALDH1A1 (0.51) | PTGESLMNA | |
| SCHEMBL4022882 | 0.77 | ALDH1A1 (0.44) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL5270466 | 0.76 | GPR35 (0.48) | BRD4GPR35LMNAACACBACACA | |
| Hydrochloric Acid SCHEMBL5267420 | 0.75 | SCN9A (0.51) | BRD4SCN9A | |
| SCHEMBL5266287 | 0.75 | SCN9A (0.45) | BRD4SCN9A | |
| SCHEMBL5212831 | 0.74 | ACACB (0.44) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL5210645 | 0.74 | KDM4E (0.45) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL5212633 | 0.74 | ALDH1A1 (0.49) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765775-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005123675-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-12-29 | — | — | WO | disclosed |